6β-Acetoxy-15,23-dideoxy-19,23-epoxyajaconine

Description

This alkaloid from Spiraea japonica L. fil. has been obtained as the crystalline hydrochloride, m.p. l14-7°C. Chemical evidence has shown it to be acetyl_x0002_spiradine G. Oxidation with chromic acid in pyridine yields a hydroxy-Iactam in which the hydroxyl and lactam groups are formed by oxidative cleavage of an intermediate alkanolamine ether.

References

Toda, Hirata., Tetrahedron Lett., 5565 (1968)