Chemical Properties
Yellow needle-shaped crystals, soluble in methanol and ethanol, derived from the rhizomes and seeds of Alnus fragrans; flowers of Alnus serrata; and rhizomes of Curcuma longa.
Uses
Alnustone is a naturally occuring compound that is found in the rhizomes of Curcuma xanthorrhiza, a plant used in Indonesian folk medicine for its analgesic effects. Alnustone exhibits anti-inflammatory, antihepatotoxic and antiemetic activities.
Definition
ChEBI: Alnustone is a diarylheptanoid.
Biological Activity
Alnustone is a diarylheptanoid isolated from Alpinia katsumadai Hayata, rhizomes of Curcuma xanthorrhiza and other plants th at exhibits anti-hyperglycemic, anti-inflammatory, antihepatotoxic and antiemetic activities. Alnustone is a potent inhibitor of the Thyroid Adenoma Associated (THADA) function, which reverses THADA-induced β-cell dysfunction and ameliorate hyperglycemia in obese mice. It significantly decreases fed blood glucose and improved glucose tolerance in mice.
target
Immunology & Inflammation related
