Uses
Used in synthetic applications of carbon-substituted iminium salts
Reactant for:
Synthesis of mutasynthons added to cultures of A. pretiosum for mutasynthetic generation of ansamitocin derivatives
Oxalic acid formation from hydroxyl radical substitutions
Cyclization to produce CRF1 receptor antagonists
Preparation, optical and electrochemical studies of thiophene end capped olig(2,3-alkylthieno[3,4-b]pyrazine)
Asymmetrical synthesis of glycosyl chlorides and bromides
Biochem/physiol Actions
Leptin is a hormone produced primarily in adipocytes, although leptin mRNA has also been identified in placenta and fetal tissues, gastric tissue and liver. Its primary site of action appears to be on neurons in the hypothalamus that are involved in regulating energy balance, appetite, and body weight. Leptin increases the production of nitric oxide in endothelial cells and stimulates angiogenesis in vitro and in vivo.Human and mouse leptin share ~84% sequence identity.
