ChemicalBook CAS DataBase List 15219-34-8

15219-34-8

Name	OXALYL BROMIDE
CAS	15219-34-8
EINECS(EC#)	239-271-7
Molecular Formula	C2Br2O2
MDL Number	MFCD00000113
Molecular Weight	215.83
MOL File	15219-34-8.mol

Synonyms

OB CAD11 CDHOB BrCOCOBr NSC 96957 OXALYL BROMO Oxaly bromide OXALYL BROMIDE Leptin from rat Oxalyl dibromide Oxalyl bromide,98% Dibromoethanedione Oxalyl broMide 97% Ethanedioyl bromide ethanedioyldibromide Oxalic acid dibromide Ethanedioyl-dibromide- oxalyl bromide solution Oxalyl broMide, 98% 25GR Ethanedioyl dibromide solution Anti-CDH11 antibody produced in goat cadherin 11, type 2, OB-cadherin (osteoblast) OXALYL BROMIDE, 2.0M SOLUTION IN DICHLOR OMETHANE

Chemical Properties

Appearance	clear yellow to yellow-green liquid
Melting point	−19 °C(lit.)
Boiling point	16-17 °C10 mm Hg(lit.)
density	1.517 g/mL at 25 °C
refractive index	n20/D 1.522(lit.)
Fp	-19°C
storage temp.	Refrigerator (+4°C)
solubility	Benzene (Slightly), Chloroform
form	Liquid
color	Clear
biological source	goat
BRN	1744437
Stability:	Moisture Sensitive
InChI	InChI=1S/C2Br2O2/c3-1(5)2(4)6
InChIKey	JAZLVNXWYDFQFE-UHFFFAOYSA-N
SMILES	C(Br)(=O)C(Br)=O
CAS DataBase Reference	15219-34-8
EPA Substance Registry System	Ethanedioyl dibromide (15219-34-8)

Safety Data

Symbol(GHS)	GHS05,GHS07
Signal word	Danger
Hazard statements	H314-H332
Precautionary statements	P261-P271-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
Hazard Codes	C,T
Risk Statements	23/24/25-34-40-29-20-14-37 less more
Safety Statements	26-36/37/39-45-28-27 less more
RIDADR	UN 3265 8/PG 2
WGK Germany	3
F	8-9
TSCA	TSCA listed
HazardClass	8
PackingGroup	II
HS Code	29171990

Hazard Information

Chemical Properties

clear yellow to yellow-green liquid

Uses

Leptin from rat has been used:

to check the effect of intranasal nerve growth factor (NGF) on NGF activity in the spinal cord of Sprague-Dawley rats
for validation of labelling for leptin-bearing cells of Sprague-Dawley rats
to study the effect of leptin on STAT3 (signal transducer and activator of transcription 3) phosphorylation in neural population of Sprague-Dawley rats
to study leptin response towards chemoreflex in nucleus of the solitary tract
in rats, to check the effect of association between leptin and neuronal nitric oxide pathway on penicillin-induced epileptiform activity

Uses

Used in synthetic applications of carbon-substituted iminium salts
Reactant for:
Synthesis of mutasynthons added to cultures of A. pretiosum for mutasynthetic generation of ansamitocin derivatives
Oxalic acid formation from hydroxyl radical substitutions
Cyclization to produce CRF1 receptor antagonists
Preparation, optical and electrochemical studies of thiophene end capped olig(2,3-alkylthieno[3,4-b]pyrazine)
Asymmetrical synthesis of glycosyl chlorides and bromides

reaction suitability

reagent type: oxidant

Biochem/physiol Actions

Leptin is a hormone produced primarily in adipocytes, although leptin mRNA has also been identified in placenta and fetal tissues, gastric tissue and liver. Its primary site of action appears to be on neurons in the hypothalamus that are involved in regulating energy balance, appetite, and body weight. Leptin increases the production of nitric oxide in endothelial cells and stimulates angiogenesis in vitro and in vivo.Human and mouse leptin share ~84% sequence identity.

Spectrum Detail

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