Uses
Xylometazoline is used for rhinitis, laryngitis, sinusitis, inflammation of antrum of
Highmore, and allergic illnesses of the nasal cavity and throat.
Uses
Adrenergic (vasoconstrictor).
Definition
ChEBI: Xylometazoline is an alkylbenzene.
brand name
Neo-Synephrine II (Sterling Winthrop); Otrivin
Hydrochloride (Ciba-Geigy).
Synthesis
Xylometazoline, 2-(4-tert-butyl-2,6-dimethylbenzyl)-2-imidazoline
(11.1.40), is also synthesized in a single reaction by cyclocondensation of 4-tert-butyl-2,6-
dimethylbenzylcyanide with ethylendiamine [43,44].