Acetophenone oxime

Description

Acetophenone oxime is a solid but slightly soluble substance. Acetophenone oxime is incompatible with strong oxidising agents, moisture, acids, and metal and alkali compounds. Acetophenone oxime on decomposition releases irritating and toxic fumes and gases. There is no published data about the hazardous polymerisation of acetophenone oxime.

Chemical Properties

WHITE TO CREAM CRYSTALLINE POWDER

Chemical Properties

Acetophenone oxime is a solid but slightly soluble substance. It is incompatible with strong oxidizing agents, moisture, acids, metal, and alkali compounds. On decomposition, acetophenone oxime releases irritating and toxic fumes and gases. There are no published data about the hazardous polymerization of acetophenone oxime.

Uses

1-Phenylethanone Oxime is a useful reagent for organic synthesis

Synthesis Reference(s)

The Journal of Organic Chemistry, 52, p. 5089, 1987 DOI: 10.1021/jo00232a005
Tetrahedron Letters, 30, p. 5763, 1989 DOI: 10.1016/S0040-4039(00)76191-0

Health Hazard

Exposures to acetophenone oxime cause irritation to the eyes, skin, and the respiratory and digestive tracts. The toxicological properties of acetophenone oxime are not been fully investigated.

Safety Profile

Poison by an unspecified route.Slightly toxic by ingestion. When heated to decomposition itemits toxic vapors of NOx.

storage

Acetophenone oxime should be kept stored in a cool, dry place and in a closed container when not in use.

Precautions

On exposures to acetophenone oxime, occupational workers should immediately fl ush the eyes with plenty of water. Workers should use proper personal protective equipment, wear appropriate gloves to prevent skin exposure, and wear appropriate protective eyeglasses or chemical safety goggles as described.