Chemical Properties
3-Aminoacetophenone is yellow to light brown crystalline powder
Uses
3'-Aminoacetophenone has potential anti-bacterial properties in addition to being used in the synthesis of selective antagonists at human A2B adenosine receptors. As well, it is used in the synthesis
of HIV-1 Integrase Inhibitors.
Uses
3′-Aminoacetophenone (3-Acetylaniline) was used as reagent during the asymmetric total synthesis of pactamycin. It was used as starting reagent during the synthesis of curcumin mimics with substituted sulfonyl group.
Definition
ChEBI: 3'-Aminoacetophenone is an aromatic ketone.
General Description
3′-Aminoacetophenone acts as bifunctional coupling reagent during the synthesis of pyrimidines.
Safety Profile
Moderately toxic by ingestion. Mddly toxic by skin contact. A skin and eye irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of NO,. See also AROMATIC AMINES.
Purification Methods
Recrystallise it from EtOH or aqueous EtOH (m 99.5o). The thiosemicarbazone has m 202-204o (from EtOH). [Beilstein 14 H 45, 14 IV 96.]
