Chemical Properties
Liquid
Uses
Barlene(R) 8S is a tertiary amine used typically as an intermediate in the manufacture of quaternary ammonium compounds.
Uses
N,N-Dimethyl-n-octylamine is used as ion-pairing agent in the quantitative estimation of thiazinamium methylsulphate in a pharmaceutical preparation by HPLC. It acts as a counterion in mobile phase for separation of tetracycline, tetracycline analogs and their potential impurities by reversed-phase ion-pair chromatography. Further, it is used in the study of chiral separations by complexation with proteins in capillary zone electrophoresis. In addition to this, it is used as a mobile phase in direct resolution and quantitation of (R)- and (S)-disopyramide
Synthesis Reference(s)
Journal of the American Chemical Society, 72, p. 3073, 1950
DOI: 10.1021/ja01163a074Tetrahedron Letters, 18, p. 1937, 1977
