Uses
CaⅡ-EDTA disodium dihydrate (Calcium disodium EDTA dihydrate) is an orally active metal chelating reagent, exhibits bactericidal activities against periodontal pathogens Aggregatibacter actinomycetemcomitans, Prevotella intermedia and Porphyromonas gingivalis[1]. CaⅡ-EDTA disodium dihydrate is effective chelating antidotes for lead- and cadmium poisoning[2][3].
References
[1] Miura, T. et al., Ca (II)-EDTA shows antimicrobial activity against periodontopathic bacteria. Journal of Biomedical Science and Engineering, 5, 10-14.
[2] Saleh SM, et al., Do Nanoparticles of Calcium Disodium EDTA Minimize the Toxic Effects of Cadmium in Female Rats Biol Trace Elem Res. 2023 Sep 18. DOI:
10.1007/s12011-023-03842-6[3] Saxena G, et al., Lead-induced oxidative stress and hematological alterations and their response to combined administration of calcium disodium EDTA with a thiol chelator in rats. J Biochem Mol Toxicol. 2004;18(4):221-33. DOI:
10.1002/jbt.20027
