(R)-p-Mentha-1,8-dien

Bezeichnung:(R)-p-Mentha-1,8-dien

CAS-Nr5989-27-5

Englisch Name:(+)-Dipentene

CBNumberCB9853935

SummenformelC10H16

Molgewicht136.23

MOL-Datei5989-27-5.mol

Synonyma

(R)-p-Mentha-1,8-dien

Carven

(R)-4-Isopropenyl-1-methylcyclohexen

(R)-p-Mentha-1,8-dien physikalisch-chemischer Eigenschaften

Schmelzpunkt	-75--73°C
Siedepunkt	176-177 °C(lit.)
alpha	112o (10% IN ETHANOL)
Dichte	0.842 g/mL at 20 °C(lit.)
Dampfdichte	4.7 (vs air)
Dampfdruck	1 mm Hg ( 20 °C)
Brechungsindex	n20/D 1.473(lit.)
FEMA	2633 \| D-LIMONENE
Flammpunkt	119 °F
storage temp.	Store below +30°C.
Löslichkeit	water: insoluble
Wichte	0.842 (20/4℃)
Farbe	Colorless to Almost colorless
Geruch (Odor)	at 100.00 %. citrus orange fresh sweet
Geruchsart	citrus
Optische Aktivität	[α]20/D +120°, neat
Explosionsgrenze	0.7-6.1%(V)
Wasserlöslichkeit	Miscible with alcohol,chloroform,ether and carbondisulfide.Immiscible with water.
Merck	14,5493
JECFA Number	1326
BRN	2204754
Stabilität	Stable. Flammable. Incompatible with strong oxidizing agents.
LogP	4.38 at 25℃
CAS Datenbank	5989-27-5(CAS DataBase Reference)
IARC	3 (Vol. 56, 73) 1999
EPA chemische Informationen	D-Limonene (5989-27-5)

Sicherheit

Kennzeichnung gefährlicher	Xi,N,Xn
R-Sätze:	10-38-43-50/53-65
S-Sätze:	24-37-60-61
RIDADR	UN 2052 3/PG 3
WGK Germany	2
RTECS-Nr.	GW6360000
F	8-10-23
Selbstentzündungstemperatur	255 °C
TSCA	Yes
HS Code	2902 19 00
HazardClass	3
PackingGroup	III
Giftige Stoffe Daten	5989-27-5(Hazardous Substances Data)
Toxizität	LD50 orally in Rabbit: > 2000 mg/kg LD50 dermal Rabbit > 2000 mg/kg

Gefahreninformationscode (GHS)

(+)-Dipentene Chemische Eigenschaften,Einsatz,Produktion Methoden

ERSCHEINUNGSBILD
FARBLOSE FLüSSIGKEIT MIT CHARAKTERISTISCHEM GERUCH.
CHEMISCHE GEFAHREN
Reagiert sehr heftig mit einem Gemisch aus Iodpentafluorid und Tetrafluorethylen unter Feuer- und Explosionsgefahr. Reagiert mit Oxidationsmitteln.
ARBEITSPLATZGRENZWERTE
TLV nicht festgelegt (ACGIH 2005).
MAK: 20 ppm, 110 mg/m? Spitzenbegrenzung: überschreitungsfaktor II(2); Sensibilisierung der Haut; Schwangerschaft: Gruppe C; (DFG 2005).
INHALATIONSGEFAHREN
Nur ungenügende Angaben vorhanden über die Geschwindigkeit, mit der eine gesundheitsschädliche Konzentration in der Luft beim Verdampfen bei 20°C erreicht wird.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION:
Die Substanz reizt die Haut und reizt leicht die Augen.
WIRKUNGEN NACH WIEDERHOLTER ODER LANGZEITEXPOSITION
Wiederholter oder andauernder Kontakt kann zu Hautsensibilisierung führen (s. Anm.).
LECKAGE
Persönliche Schutzausrüstung: Atemschutzgerät, P1-Filter für inerte Partikel. NICHT in die Umwelt gelangen lassen. Ausgelaufene Flüssigkeit möglichst in abdichtbaren Behältern sammeln. Reste mit Sand oder inertem Absorptionsmittel aufnehmen und an einen sicheren Ort bringen.
R-Sätze Betriebsanweisung:
R10:Entzündlich.
R38:Reizt die Haut.
R43:Sensibilisierung durch Hautkontakt möglich.
R50/53:Sehr giftig für Wasserorganismen, kann in Gewässern längerfristig schädliche Wirkungen haben.
S-Sätze Betriebsanweisung:
S24:Berührung mit der Haut vermeiden.
S37:Geeignete Schutzhandschuhe tragen.
S60:Dieses Produkt und sein Behälter sind als gefährlicher Abfall zu entsorgen.
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
Beschreibung
d-Limonene has a pleasant, lemon-like odors free from campho raceous and turpentine-like. d-Limonene may be obtained by steam distillation of citrus peels and pulp resulting from the pro duction of juice and cold-pressed oils, or from deterpenation of citrus oils; it is sometimes redistilled.
The most important and widespread terpene; it is known in the el and I- optically active forms and in the optically inactive dl-form (known as dipentene); it has been reported found in more than 300 essential oils in amounts ranging from 90 - 95% (lemon, orange, mandarin) to as low as 1% (palmarosa);1 the most widespread form is the d-limonene, followed by the racemic form, and then ι- limonene.
Beschreibung
(+)-Limonene is a monoterpene that has been found in citrus oils and Cannabis and has diverse biological activities, including anticancer, antimicrobial, antioxidant, anti-inflammatory, and chemoprotective properties. It inhibits the growth of bacteria including S. aureus, B. cereus, E. faecalis, E. coli, P. aeruginosa, K. pneumoniae, M. catarrhalis, and C. neoformans with MIC values ranging from 3 to 27 mg/ml. In a human BGC-823 gastric cancer nude mouse orthotopic transplantation model, (+)-limonene inhibits tumor growth by 47.6% compared to controls and reduces the number of metastases in the liver, peritoneum, and other organs when administered by gastric perfusion at a dose of 15 ml/kg of a 1% emulsion. Dietary administration of (+)-limonene (5 and 10% in chow) reverses doxorubicin-induced decreases in glutathione (GSH) levels in rat kidney. Formulations containing (+)-limonene have been used as flavoring and fragrance agents and in the treatment of gallstones, heartburn, and gastroesophageal reflux disorder.
Chemische Eigenschaften
colourless liquid
Chemische Eigenschaften
d-, l- or dl-Limonene has a pleasant, lemon-like odor free from camphoraceous and turpentine-like notes. Limonene is the most important and widespread terpene; it is known in the d- and l- optically active forms and in the optically inactive dl-form (known as dipentene).
Occurrence
It has been reported found in more than 300 essential oils in amounts ranging from 90 to 95% (lemon, orange, mandarin) to as low as 1% (palmarosa); the most widespread form is the d-limonene, followed by the racemic form and then l-limo nene. Also reported found in ginger, nutmeg, pepper, mace, hop oil, coriander seed, calamus, dill herb, caraway seed and rosemary.
Verwenden
(R)-(+)-Limonene has been used to investigate the in vitro and in vivo action of limonene against Leishmania species.
Verwenden
Reference Standard in the analysis of herbal medicinal products
Verwenden
Chiral building block. Biodegradable solvent. Limonene is used as a solvent for filament-fused 3D printing, in cosmetic products, as a fragrance and as a biofuel. It is useful to promote weight loss, prevent cancer, treat cancer and treat bronchitis. It also finds use in foods, beverages, chewing gum, as a flavoring agent and a shrinking agent to dissolve polystyrene. It acts as a chiral intermediate for natural product synthesis.
Definition
ChEBI: An optically active form of limonene having (4R)-configuration.
synthetische
d-Limonene may be obtained by steam distillation of citrus peels and pulp resulting from the production of juice and cold pressed oils, or from deterpenation of citrus oils; it is sometimes redistilled.
Aroma threshold values
Detection: 4 to 229 ppb
Taste threshold values
Taste characteristics at 30 ppm: sweet, orange, citrus and terpy.
Allgemeine Beschreibung
Clear colorless mobile liquid with a pleasant lemon-like odor.
Air & Water Reaktionen
Highly flammable. Insoluble in water.
Reaktivität anzeigen
(+)-Dipentene is sensitive to exposure to light. Atmospheric oxidation can occur. (+)-Dipentene is incompatible with strong oxidizing agents. (+)-Dipentene reacts violently with (iodine pentafluoride + tetrafluoroethylene). With dry hydrogen chloride or hydrogen bromide, (+)-Dipentene forms monohalides. With aqueous hydrogen chloride or hydrogen bromide, (+)-Dipentene forms the dihalide.
Brandgefahr
(+)-Dipentene is combustible.
Landwirtschaftliche Anwendung
Insecticide, Animal and insect repellant, Slimicide: Used as an insecticide, insect repellent, and animal repellent. Not listed for use in EU countries. Registered for use in the U.S., Canada and other countries. There are 49 global suppliers.
Handelsname
BUGAWAY®[C]; BUGCHASER®[C]; CARVENE®; DOO-NOT®; HOLIDAY FIRE ANT KILLER®
Biochem/physiol Actions
Limonene is a cyclie terpene from Chinese medicinal herb essential oils used in the synthesis of carvone. Limonene may be used as a shrinking agent to dissolve polystyrene. Limonene may be used in various insecticidal and insect repellant applications.
Kontakt-Allergie
d-Limonene is contained in Citrus species such as citrus, orange, mandarin, and bergamot. d-limonene, used as a solvent, may be found in cleansing or in degreasing agents. Its sensitizing potential increases with prolonged air contact, which induces oxidation and leads to oxidation products. The presence of d-limonene has to be mentioned by name in cosmetics of the EU.

(+)-Dipentene Upstream-Materialien And Downstream Produkte

(R)-p-Mentha-1,8-dien Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

5989-27-5, (+)-Dipentene Verwandte Suche:

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