2,5-Dichlorobenzophenone

Bezeichnung:2,5-Dichlorobenzophenone

CAS-Nr16611-67-9

Englisch Name:2,5-Dichlorobenzophenone

CBNumberCB9699315

SummenformelC13H8Cl2O

Molgewicht251.11

MOL-Datei16611-67-9.mol

2,5-Dichlorobenzophenone physikalisch-chemischer Eigenschaften

Schmelzpunkt	87-88°C
Siedepunkt	240-260 °C
Dichte	1.311±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
Aggregatzustand	crystals
Farbe	Off-white to brown
CAS Datenbank	16611-67-9(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36/37/39
Hazard Note	Harmful
HazardClass	IRRITANT
HS Code	2914790090

Gefahreninformationscode (GHS)

2,5-Dichlorobenzophenone Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Verwenden
2,5-Dichlorobenzophenones can be used as starting materials for general, pharmaceutical and polymer synthesis. For example, using such compounds to prepare substituted para-polyphenylenes should proceed readily by metal-catalyzed aryl coupling of the 2,5-dichlorophenyl group of these compounds. Polyphenylenes formed from these compounds will have pendant side groups comprising the carbonyl, and the aryl or pyridyl group bonded thereto.
Synthese
To a 22 L, three-necked flask fitted with a thermometer, mechanical stirrer and a Vigreux column connected to an aqueous NaOH scrubbing tower, was added 1,4-dichlorobenzene (3 Kg, 26.4 mol) and benzoyl chloride (2.6 Kg, 18.55 mol). The mixture was heated to 80° C. to give a homogeneous solution. Aluminum chloride (5.5 Kg, 41.25 mol) was added over 12 min. with stirring. (The molar ratio of reactants was 2.2:1.4:1.0 (AlCl3 : Dichlorobenzene: Benzoyl Chloride)). The resulting mixture was heated to 140° C. over 60 min, followed by heating to 175° C. over 30 min. The heating was stopped at 175° C. The mixture was allowed to cool to 80° C. over two hours and poured into a well-stirred mixture of ice and water (ca. 25 L water and 15 Kg of ice) over 30 min. The organic solid was collected by filtration and dissolved in 7 L of toluene. The solution was washed with aqueous sodium bicarbonate and dried. Toluene was removed by distillation. Pure 2,5-dichlorobenzophenone was isolated in 80% yield after recrystallization from hexane and toluene.

2,5-Dichlorobenzophenone Upstream-Materialien And Downstream Produkte

2,5-Dichlorobenzophenone Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

16611-67-9, 2,5-Dichlorobenzophenone Verwandte Suche:

Send Inquriy