Benzylnicotinat

Bezeichnung:Benzylnicotinat

CAS-Nr94-44-0

Englisch Name:Benzyl nicotinate

CBNumberCB9363852

SummenformelC13H11NO2

Molgewicht213.23

MOL-Datei94-44-0.mol

Synonyma

Benzylnicotinat

Benzylnicotinat physikalisch-chemischer Eigenschaften

Schmelzpunkt	24 °C (lit.)
Siedepunkt	177 °C/8 mmHg (lit.)
Dichte	1,1165 g/cm³
Brechungsindex	n20/D 1.570
Flammpunkt	170°C
storage temp.	Sealed in dry,Room Temperature
Löslichkeit	Chloroform (Sparingly), Methanol (Slightly)
Aggregatzustand	<24°C Solid,>24°C Liquid
pka	3.16±0.10(Predicted)
Farbe	Colourless to Light Beige
Merck	14,6526
BRN	159169
LogP	2.400
CAS Datenbank	94-44-0(CAS DataBase Reference)
NIST chemische Informationen	Nicotinic acid, benzyl ester(94-44-0)
EPA chemische Informationen	3-Pyridinecarboxylic acid, phenylmethyl ester (94-44-0)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/38
S-Sätze:	26
WGK Germany	2
RTECS-Nr.	QT0850000
F	8
TSCA	Yes
HS Code	2933399990

Gefahreninformationscode (GHS)

Benzyl nicotinate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/38:Reizt die Augen und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
Benzyl nicotinate is a benzyl ester resulting from the formal condensation of the carboxy group of nicotinic acid with benzyl alcohol. It derives from a nicotinic acid. It is a vasodilator agent and is also generally used in cosmetics and drugs.It has been used as a rubefacient.
Benzyl nicotinate can be used for the synthesis of benzylpalladium complexes to be used as catalysts for the substitution of olefins with benzylic groups.
Verwenden
benzyl nicotinate can increase skin oxygenation—thanks to vasodilatation properties—and help stimulate the healing process of wounded skin. It is an ester form of niacin (vitamin B), benzyl alcohol, and nicotinic acid.
Verwenden
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Verwenden
Benzyl nicotinate can be used for the synthesis of benzylpalladium complexes to be used as catalysts for the substitution of olefins with benzylic groups.
Definition
ChEBI: A benzyl ester resulting from the formal condensation of the carboxy group of nicotinic acid with benzyl alcohol. It has been used as a rubefacient.
Synthesis Reference(s)
Synthetic Communications, 14, p. 515, 1984 DOI: 10.1080/00397918408059573
Allgemeine Beschreibung
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Benzyl Nicotinate is a medication widely used as a vasodilator, that widens blood vessels. It basically oxygenates and flushes the skin′s capillaries.
Clinical Use
Benzyl nicotinate is used in combination with heparin in the treatment of inflammation of vein (thrombophlebitis), pain in dilated veins area, pains and cramps in the leg muscles, disturbances of lymph circulation, traffic and sports related injuries, postoperative and posttraumatic scars, non-joint rheumatism or soft tissue rheumatism.
Nebenwirkungen
The common side-effects of Heparin+benzyl Nicotinate are skin irritation, redness, burning sensation, and itching. These side-effects are usually mild and temporary.

Benzyl nicotinate Upstream-Materialien And Downstream Produkte

Benzylnicotinat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

94-44-0, Benzyl nicotinate Verwandte Suche:

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