Tamsulosin hydrochloride

Tamsulosin hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

  White to Off-White Solid

• Verwenden

  Tamsulosin hydrochloride is a specific ;1-adrenoceptor antagonist. Used in the treatment of benign prostatic hypertrophy.

• Verwenden

  Tamsulosin is a specific α1-adrenoceptor antagonist. Used in the treatment of benign prostatic hypertrophy.

• Clinical Use

  Treatment of benign prostatic hyperplasia

• Arzneimittelwechselwirkung

  Potentially hazardous interactions with other drugs
  Anaesthetics: enhanced hypotensive effect.
  Antidepressants: enhanced hypotensive effect with MAOIs.
  Antifungals: concentration increased by ketoconazole.
  Avanafil, vardenafil, sildenafil and tadalafil: enhanced hypotensive effect, avoid concomitant use.
  Beta-blockers: enhanced hypotensive effect; increased risk of first dose hypotensive effect.
  Calcium-channel blockers: enhanced hypotensive effect; increased risk of first dose hypotensive effect.
  Diuretics: enhanced hypotensive effect; increased risk of first dose hypotensive effect.
  Moxisylyte: possibly severe postural hypotension.

• Stoffwechsel

  Tamsulosin is metabolised slowly in the liver primarily by the cytochrome P450 isoenzymes CYP2D6 and CYP3A4; it is excreted mainly in the urine as metabolites and some unchanged drug

Tamsulosin hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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