N8,N8,3-Trimethyl-2,8-phenazin-diaminmonohydrochlorid

Bezeichnung:N8,N8,3-Trimethyl-2,8-phenazin-diaminmonohydrochlorid

CAS-Nr553-24-2

Englisch Name:Neutral Red

CBNumberCB7853810

SummenformelC15H17ClN4

Molgewicht288.78

MOL-Datei553-24-2.mol

Synonyma

N8,N8,3-Trimethyl-2,8-phenazindiaminmonohydrochlorid

N8,N8,3-Trimethyl-2,8-phenazin-diaminmonohydrochlorid

N8,N8,3-Trimethyl-2,8-phenazin-diaminmonohydrochlorid physikalisch-chemischer Eigenschaften

Schmelzpunkt	290 °C (dec.) (lit.)
Siedepunkt	441.31°C (rough estimate)
Dichte	1.1590 (rough estimate)
Brechungsindex	1.6110 (estimate)
storage temp.	Store at +5°C to +30°C.
Löslichkeit	H2O: soluble10mg/mL
Aggregatzustand	Solid
Colour Index	50040
pka	6.7, 7.4(at 25℃)
Farbe	Very dark green
Säure-Base-Indikators(pH-Indikatoren)	6.8(red)-8(yellow)
PH	3.1 (10g/l, H2O, 20℃)
Geruch (Odor)	Odorless
Wasserlöslichkeit	50 g/L
maximale Wellenlänge (λmax)	540nm, 533nm, 544nm, 529nm, 454nm
Merck	14,6488
BRN	3918740
Stabilität	Stable. Incompatible with strong oxidizing agents.
Biologische Anwendungen	Detecting pathogens,bacterial infections; treating age-related macular degeneration,burns,cancer,diabetes,obesity,fungal infections,viral diseases
Major Application	Fuel cell power generation system, liquid crystal displays, solor cells, sensors, thermochromic materials, coloring wood, detergents, assessment of tobacco smoke, cosmetics, detect bacterial infections, multidrug resistance inhibitors, treatment of burns, endodontic, diabetes, obesity, cancer, age-related macular degeneration, viral diseases
CAS Datenbank	553-24-2(CAS DataBase Reference)
EPA chemische Informationen	Neutral Red (553-24-2)

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi
R-Sätze:	68-36/37/38
S-Sätze:	36/37-37/39-36-26-24/25
WGK Germany	3
RTECS-Nr.	SG1400000
TSCA	Yes
HS Code	32041300
Toxizität	LD50 intraperitoneal in mouse: 432mg/kg

Gefahreninformationscode (GHS)

Neutral Red Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R68:Irreversibler Schaden möglich.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
dark green powder
Verwenden
Can be used as a vital stain, to stain living cells.
Verwenden
Neutral Red is a common histology stain used to determine cell viability. It is also used as indicator for nitrogen determination; pH indicator; Dyes and metabolites.
Application
Transition of pH Indicator: pH 6.8 - 8.0, red to yellow. Basic red 5 is a dye used in histology for staining nuclei. It is also a pH indicator. As such it is used in microbial culture media for differentation of bacteria. For example MacConkey agar contains it and lactose. Acidification by lactic acid turns on the Basic red 5. Therefore, colonies formed by bacteria that ferment lactose into lactic acid will turn red and stand out from the pale colonies of non-lactose-fermenting bacteria. Basic red 5 is also used in cell viability tests based on the ability to incorporate and bind it.
Definition
ChEBI: Neutral red is a hydrochloride obtained by combining the free base of neutral red with one equivalent of hydrochloric acid. Neutral red acts as a pH indicator, changing from red to yellow between pH 6.8 and 8.0. It has a role as a dye, an acid-base indicator and a two-colour indicator. It contains a neutral red(1+).
synthetische
(a) N,N-dimethyl-4-nitrosobenzenamine?and 4-Methylbenzene-1,3-diamine???reaction, form Toluylene Blue (Basic Dye, C.I. 49410), heating make cyclization; (b) oxidation N1,N1-dimethylbenzene-1,4-diamine?, and 4-Methylbenzene-1,3-diamine mixture.
Allgemeine Beschreibung
Neutral red (C.I. 50040) is a protonated diaminophenazine dye. It is aminodimethylaminomethylphenazinehydrochloride, C15H17N4Cl.
Biochem/physiol Actions
Neutral red is a widely used cationic fluorochrome that is known to accumulate in the Golgi complex and nuclei after first staining lysosomes.
Biotechnological Applications
Neutral Red is a non-toxic stain used for studies of living cells, for example to observe plasmolysis. The stain is used as an aqueous solution (0.1 %, w/v) and stains lipids in vacuoles and certain cell walls.
Lager
+4°C
Staining Procedures
Neutral Red is a non-toxic stain used for studies of living cells, for example to observe plasmolysis. The stain is used as an aqueous solution (0.1 %, w/v) and stains lipids in vacuoles and certain cell walls.
Properties and Applications
red light purple and red. Soluble in water is cherry red, soluble in ethanol for product red colour with red fluorescent light brown. The strong sulfuric acid for green, blue for diluted, and then into a product red. The dye solution to join strong sodium hydroxide solution have yellow brown precipitation.
läuterung methode
In aqueous solution it is red at pH 6.8 and yellow at pH 8.0. [Beilstein 25 III/IV 3054.]

Neutral Red Upstream-Materialien And Downstream Produkte

N8,N8,3-Trimethyl-2,8-phenazin-diaminmonohydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

553-24-2, Neutral Red Verwandte Suche:

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