4-Bromphenol

Bezeichnung:4-Bromphenol

CAS-Nr106-41-2

Englisch Name:4-Bromophenol

CBNumberCB7181317

SummenformelC6H5BrO

Molgewicht173.01

MOL-Datei106-41-2.mol

Synonyma

4-Bromphenol

4-Bromphenol physikalisch-chemischer Eigenschaften

Schmelzpunkt	61-64 °C (lit.)
Siedepunkt	235-236 °C (lit.)
Dichte	1.84
Brechungsindex	1.5085 (estimate)
Flammpunkt	235-238°C
storage temp.	room temp
Löslichkeit	14g/l
Aggregatzustand	Crystalline Solid
pka	9.37(at 25℃)
Farbe	Pinkish-brown
Wasserlöslichkeit	It is insoluble in water. It is soluble in 5%ethanol.
maximale Wellenlänge (λmax)	282nm(EtOH)(lit.)
Merck	14,1428
BRN	1680024
CAS Datenbank	106-41-2(CAS DataBase Reference)
NIST chemische Informationen	4-Bromophenol(106-41-2)
EPA chemische Informationen	Phenol, 4-bromo- (106-41-2)

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi
R-Sätze:	22-36/37/38-20/21/22
S-Sätze:	26-37/39-36
RIDADR	2811
WGK Germany	2
RTECS-Nr.	SJ7960000
F	8-10-23
Hazard Note	Irritant
TSCA	Yes
HazardClass	6.1(b)
PackingGroup	III
HS Code	29081000
Giftige Stoffe Daten	106-41-2(Hazardous Substances Data)
Toxizität	mouse,LD50,intraperitoneal,411mg/kg (411mg/kg),Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 44(12), Pg. 19, 1979.

Gefahreninformationscode (GHS)

4-Bromophenol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
4-Bromophenol is a pinkish-brown crystalline solid. four-sided biconical crystal precipitated from ether or chloroform. The melting point is 66.4 ℃, and a small amount of water can reduce the melting point a lot. Soluble in water, chloroform, easily soluble in ethanol, ether and glacial acetic acid, soluble in 7 parts of water.
Verwenden
4-Bromophenol is used as an intermediate in medicine grade. It is also used as a phenol that is used in Stille reactions. It is used in the intermediate of organic synthesis, flame retardant and pharmaceutical industry.
Application
4-Bromophenol is a phenolic derivative that It can used as a reagent in Stille reactions or Intermediates of Liquid Crystals.
synthetische
4-Bromophenol is synthesized by bromination of phenol. The bromine and carbon disulfide solution was added to the phenolic carbon disulfide solution, and the addition was started below 5°C, and the addition was completed under stirring for 2 hours. Phenol and bromine are approximately equimolar ingredients. Distill the reactant to remove carbon disulfide, and then conduct fractional distillation under reduced pressure to collect fractions at 145-150°C (3.32-3.99kPa) to obtain the product. Yield 80-84%.
Definition
ChEBI: 4-bromophenol is a bromophenol containing only hydroxy and bromo substituents that are para to one another. It has a role as a mouse metabolite, a persistent organic pollutant, a human xenobiotic metabolite, a rat metabolite, a human urinary metabolite and a marine metabolite.
Synthesis Reference(s)
Tetrahedron, 45, p. 7869, 1989 DOI: 10.1016/S0040-4020(01)85800-2
The Journal of Organic Chemistry, 23, p. 280, 1958 DOI: 10.1021/jo01096a033
läuterung methode
Crystallise the phenol from CHCl3, CCl4, pet ether (b 40-60o), or water and dry it at 70o under vacuum for 2hours. [Beilstein 6 IV 1043.]

4-Bromophenol Upstream-Materialien And Downstream Produkte

4-Bromphenol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

106-41-2, 4-Bromophenol Verwandte Suche:

Send Inquriy