Bornan-2-on

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Achtung

• Gefahrenhinweise

  H228：Entzündbarer Feststoff.

  H315：Verursacht Hautreizungen.

  H317：Kann allergische Hautreaktionen verursachen.

  H318：Verursacht schwere Augenschäden.

  H332：Gesundheitsschädlich bei Einatmen.

  H371：Kann die Organe schädigen.

  H411：Giftig für Wasserorganismen, mit langfristiger Wirkung.

• Sicherheit

  P210：Von Hitze, heißen Oberflächen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen.

  P273：Freisetzung in die Umwelt vermeiden.

  P280：Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

  P305+P351+P338：BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Camphor Chemische Eigenschaften,Einsatz,Produktion Methoden

• ERSCHEINUNGSBILD

  FARBLOSEODER WEISSE KRISTALLE MIT CHARAKTERISTISCHEM GERUCH.

• PHYSIKALISCHE GEFAHREN

  Staubexplosion der pulverisierten oder granulierten Substanz in Gemischen mit Luft möglich.

• CHEMISCHE GEFAHREN

  Zersetzung beim Verbrennen unter Bildung giftiger Gaseund reizender Rauche. Reagiert sehr heftig mit starken Oxidationsmitteln, starken Reduktionsmittelnund chlorhaltigen Lösemitteln unter Feuer- und Explosionsgefahr.

• ARBEITSPLATZGRENZWERTE

  TLV: 2 ppm (als TWA); 3 ppm (als STEL); Krebskategorie A4 (nicht klassifizierbar als krebserzeugend für den Menschen); (ACGIH 2005).
  MAK: 2 ppm, 13 mg/m? Spitzenbegrenzung: überschreitungsfaktor II(2); (DFG 2005).
  

• AUFNAHMEWEGE

  Aufnahme in den Körper durch Inhalation und durch Verschlucken.

• INHALATIONSGEFAHREN

  Beim Verdampfen bei Raumtemperatur tritt eine gesundheitsschädliche Kontamination der Luft ein.

• WIRKUNGEN BEI KURZZEITEXPOSITION

  WIRKUNGEN BEI KURZZEITEXPOSITION:
  Die Substanz reizt die Augen, die Haut und die Atemwege. Möglich sind Auswirkungen auf das Zentralnervensystem mit nachfolgenden Krämpfenund Atemdepression. Aufnahme durch Verschlucken kann zum Tod führen.

• LECKAGE

  Belüftung. Zündquellen entfernen. Verschüttetes Material in abgedeckten Behältern sammeln; falls erforderlich durch Anfeuchten Staubentwicklung verhindern. Persönliche Schutzausrüstung: Atemschutzgerät, A/P2-Filter für organische Dämpfe und schädlichen Staub.

• R-Sätze Betriebsanweisung:

  R11:Leichtentzündlich.
  R22:Gesundheitsschädlich beim Verschlucken.
  R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
  R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.

• S-Sätze Betriebsanweisung:

  S16:Von Zündquellen fernhalten - Nicht rauchen.
  S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
  S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.

• Beschreibung

  Camphor was recorded in the ancient books of traditional Chinese medicine, such as Pin Hui Jing Yao, Ben Cao Gang Mu, and Sheng Lian Fang. There has been a long history for traditional Chinese medicine to use camphor.

• Chemische Eigenschaften

  Both optical isomers are found widely in nature, with (+)-camphor being the more abundant. It is, for example, the main component of oils obtained from the camphor tree C. camphora. Camphor is produced by fractional distillation and crystallization of camphor oil or, synthetically, by dehydrogenation of isoborneol over a copper catalyst.
  Due to its characteristic penetrating, slightly minty odor, camphor is only used in perfuming industrial products. It is far more important as a plasticizer.

• Chemische Eigenschaften

  Camphor, C1oH160, also known as d-2-camphanone, Japan camphor, laurel camphor,Formosa camphor,and gumcamphor,is a terpene ketone. It is colourless solid with a characteristic odour that is obtained from the wood and bark of the camphor tree and is soluble in water and alcohol. It has two optically active forms (dextro and levo) and an optically inactive mixture (racemic) of these two forms. Camphor is used in pharmaceuticals,in disinfectants, in explosives,and to harden nitrocellulose plastics.

• Chemische Eigenschaften

  Camphor is a colorless glassy solid. Penetrating, characteristic odor.

• Physikalische Eigenschaften

  Colorless to white, flammable granules, crystals or waxy semi-solid with a strong, penetrating, fragrant or aromatic odor. Odor threshold concentration is 0.27 ppm (quoted, Amoore and Hautala, 1983).

• History

  The research and development process of camphor has gone through from the natural product extraction to the modern chemical drug synthesis. For a long time, the Chinese extracted camphor mainly from camphor tree (Cinnamomum camphora), root bark of bodinier cinnamon, and Yunnan camphor tree. With the development of chemical industry, human beings started to use chemical synthesis methods to obtain a large amount of camphor. At present, the chemical synthesis process of camphor in China has been well developed. The synthetic camphor is divided into industrial and pharmaceutical grades. The industrial grade camphor has a content of up to 96% or higher, and the pharmaceutical grade camphor with high purity can meet the standard of pharmacopeia.

• Verwenden

  camphor (Cinnamomum camphora) is credited with anesthetic, antiinflammatory, antiseptic, astringent, cooling, and refreshing properties, and thought to be slightly stimulating to blood circulation and function. once absorbed by the subcutaneous tissue, it combines in the body with glucoronic acid and is released through the urine. Camphor is effective for oily and acne skin treatment, and has a scent similar to eucalyptus. In high concentrations, it can be an irritant and numb the peripheral sensory nerves. natural camphor is derived from an evergreen tree indigenous to Asia, although now its synthetic substitute is often used.

• Verwenden

  Antipruritic.

• Verwenden

  dl-Camphor is used as a plasticizer for celluloseesters and ethers; in the manufacture ofplastics and cymene; in cosmetics, lacquers,medicine, explosives, and pyrotechnics; andas a moth repellent.

• Definition

  camphor: A white crystalline cyclicketone, C₁₀H₁₆O; r.d. 0.99; m.p.179°C; b.p. 204°C. It was formerly obtainedfrom the wood of the Formosancamphor tree, but can now besynthesized. The compound has acharacteristic odour associated withits use in mothballs. It is a plasticizerin celluloid.

• Definition

  A naturally- occurring white organic compound with a characteristic penetrating odor. It is a cyclic compound and a ketone, formerly obtained from the wood of the camphor tree but now made synthetically. Camphor is used as a platicizer for celluloid and as an insecticide against clothes moths.

• Indications

  Camphor is a ketone which, when applied in 1% to 3% concentration, has mild antipruritic effects through its anesthetic and counterirritant properties. Counterirritants are substances that, by inducing other sensations such as coolness or warmth, ‘‘crowd out’’ the perception of pain or itch. Camphor is used in various OTC topical analgesic products in concentrations as high as 9%.

• Definition

  A ketone occurring naturally in the wood of the cam- phor tree (Cinnamomum camphora).

• Trademarks

  Anbesol;Cresophene;Dasin;Ddd;Endrine;Makatussin;Mentol sedans sulfamidad;Nasello;Resol;Root bark oil;Spirit of camphor;Tcp;Tetesept;Topic.

• Weltgesundheitsorganisation (WHO)

  Camphor, an aromatic crystalline substance with mild local anaesthetic activity, is available in preparations for both external application and inhalation. The use of such preparations has precipitated convulsions in susceptible infants. This has led several regulatory authorities to require the inclusion of appropriate warnings on labelling.

• Synthesis Reference(s)

  The Journal of Organic Chemistry, 41, p. 3329, 1976 DOI: 10.1021/jo00882a030

• Allgemeine Beschreibung

  A colorless or white colored crystalline powder with a strong mothball-like odor. About the same density as water. Emits flammable vapors above 150°F. Used to make moth proofings, pharmaceuticals, and flavorings.

• Air & Water Reaktionen

  Highly flammable. Slightly soluble in water.

• Reaktivität anzeigen

  Naphthalene, Camphor, glycerol, or turpentine will react violently with chromic anhydride [Haz. Chem. Data 1967 p. 68].

• Hazard

  Evolves flammable and explosive vapors when heated. Eye and upper respiratory tract irri- tant, and anosmia. Questionable carcinogen.

• Health Hazard

  Fire may produce irritating and/or toxic gases. Contact may cause burns to skin and eyes. Contact with molten substance may cause severe burns to skin and eyes. Runoff from fire control may cause pollution.

• Health Hazard

  Vapors of camphor can irritate the eyes, nose,and throat. In humans, such irritation may be felt at >3 ppm concentration. Prolongedexposure can cause headache, dizziness, andloss of sense of smell. Ingestion can causeheadache, nausea, vomiting, and diarrhea,and at high dosages can lead to convulsion,dyspnea, and coma. High dosages can beharmful to gastrointestinal tracts, kidney,and brain.
  LD50 value, intraperitoneal (mice): 3000mg/kg.

• Brandgefahr

  Flammable/combustible material. May be ignited by friction, heat, sparks or flames. Some may burn rapidly with flare burning effect. Powders, dusts, shavings, borings, turnings or cuttings may explode or burn with explosive violence. Substance may be transported in a molten form at a temperature that may be above its flash point. May re-ignite after fire is extinguished.

• Pharmakologie

  Camphor is toxic to human. Overdose of camphor can cause irritability, drowsiness, muscle spasms, vomiting, convulsions, epilepsy, and other symptoms. The lethal dose of camphor is 50–500 mg/kg (oral administration). In general, 2 g of camphor can cause serious toxicity, and 4 g of camphor will produce fatal toxicity.
  Camphor can cause a cold sensation similar to mint when applied to human skin. In addition, it has a slightly local anesthetic effect. It can act on the gastrointestinal mucosa to produce a certain degree of stimulating effect. An appropriate dose of camphor can make people feel warm and comfortable in the stomach, but high dose of camphor will cause nausea and vomiting reaction. The effect of camphor on the central nervous system is obvious. It can act on the motor area of cerebral cortex and brain stem to produce the epilepsy-like seizures.
  It is generally believed that camphor may have some therapeutic effects on patients with acute heart failure or recurrent collapse. A low dose (50 mg) may treat mild heart fatigue and other illnesses. The oxidized camphor metabolite has a more obvious cardiotonic, hypertensive, and respiratory excitement effects.
  Camphor can be absorbed by the body after oral administration easily through the mucous, subcutaneous, and muscle. The in vivo metabolism of camphor occurs mainly in the liver. It is firstly oxidized into camphorol and then goes through phase II metabolism to produce glucuronide conjugate with glucuronic acid. Finally, the vast majority of glucuronide conjugate is excreted from the urine.

• Clinical Use

  Camphor is mainly used for the treatment of pruritic skin diseases, fibrous tissue inflammation, neuralgia, and influenza.

• Sicherheitsprofil

  A human poison by ingestion and possibly other routes. An experimental poison by inhalation, subcutaneous, and intraperitoneal routes. A local irritant. Ingestion causes nausea, vomiting, dizziness, excitation, and convulsions. Mutation data reported. Used

• Toxikologie

  Camphor is a very toxic compound which can prove fatal for infants and children on ingestion even in very small doses. Camphor products are toxic and especially dangerous to young children. Mouthing or eating camphor can cause seizures. Applying balms or ointments in large amounts and adding it to the water of a room humidifier may also cause children to seize. The onset of symptoms may occur very quickly - as early as 5 to 20 minutes.

• mögliche Exposition

  Camphor, a natural product, is used as a plasticizer for cellulose esters and ethers; it is used in lacquers and varnishes; and in explosives and pyrotechnics formulations. It is used as a moth repellent and as a medicinal.

• Erste Hilfe

  If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.

• Carcinogenicity

  Camphor was not teratogenic to rats or rabbits when administered orally during the fetal period of organogenesis at doses up to 1000mg/kg body weight (bw)/day or 681mg/kg bw/day, respectively.9 Signs of maternal toxicity included clonic convulsions, reduced motility, and reduced body weight gain in rats and reduced food consumption and body weight gain in rabbits.

• Source

  Major component in pine oil (quoted, Verschueren, 1983). Also present in a variety of rosemary shoots (330–3,290 ppm) (Soriano-Cano et al., 1993), anise-scented basil leaves (1,785 ppm) (Brophy et al., 1993), Iberian savory leaves (2,660 ppm) (Arrebola et al., 1994), African blue basil shoots (7,000 ppm), Greek sage (160–5,040 ppm), Montane Mountain mint (3,395–3,880 ppm), yarrow leaves (45–1,780 ppm), and coriander (100–1,300 ppm) (Duke, 1992).

• Lager

  Color Code—Red: Flammability Hazard: Store ina flammable materials storage area. Prior to working withcamphor you should be trained on its proper handling andstorage. Before entering confined space where this chemicalmay be present, check to make sure that an explosive concentration does not exist. Camphor must be stored to avoidcontact with oxidizers, such as permanganates, nitrates, peroxides, chlorates, and perchlorates, and especially chromicanhydride since violent reactions occur. Store in tightlyclosed containers in a cool, well-ventilated area away fromheat, sparks, or flame. Sources of ignition, such as smokingand open flames are prohibited where camphor is used, handled, or stored in a manner that could create a potential fireor explosion hazard.

• Versand/Shipping

  UN2717 Camphor, synthetic, Hazard Class: 4.1; Labels: 4.1-Flammable solid. UN1130 camphor oil, Hazard Class: 3; Labels: 3-Flammable liquid

• Inkompatibilitäten

  May form explosive mixture with air. Violent, possibly explosive, reaction with strong oxidizers, especially chromic anhydride, potassium permanganate. May accumulate static electrical charges, and may cause ignition of its vapors.

• Waste disposal

  ncineration of a solution in a flammable solven.

Camphor Upstream-Materialien And Downstream Produkte

Bornan-2-on Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(644)Suppliers

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