Thioflavine T

Bezeichnung:Thioflavine T

CAS-Nr2390-54-7

Englisch Name:Thioflavine T

CBNumberCB6676791

SummenformelC17H19ClN2S

Molgewicht318.86

MOL-Datei2390-54-7.mol

Thioflavine T physikalisch-chemischer Eigenschaften

Schmelzpunkt	211-212 °C (decomp)
Dichte	1.301g/cm3 at 20℃
Dampfdruck	0Pa at 25℃
storage temp.	Store below +30°C.
Löslichkeit	methanol: soluble1mg/mL
Colour Index	49005
Aggregatzustand	Powder
Farbe	Yellow to ochre-yellow
BRN	3922452
LogP	3.02 at 25℃ and pH7.98
CAS Datenbank	2390-54-7(CAS DataBase Reference)
EPA chemische Informationen	Benzothiazolium, 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-, chloride (2390-54-7)

Sicherheit

S-Sätze:	24/25
RIDADR	2811
WGK Germany	3
TSCA	Yes
HazardClass	6.1(b)
PackingGroup	III
HS Code	32041300

Gefahreninformationscode (GHS)

Thioflavine T Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
yellow to ochre-yellow powder
Verwenden
A dye used to visualize beta-amyloid plaques, like those associated with Alzheimer's Disease
Verwenden
Textile dyeing, fluorescent sign paints, in combination with green or blue pigments to produce brilliant greens, phosphotungstic pigments.
Definition
ChEBI: Thioflavine T is an organic chloride salt having 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium as the counterion. It is widely used to visualise and quantify the presence of amyloids, both in vitro and in vivo. It has a role as a fluorochrome, a histological dye and a geroprotector. It contains a thioflavin T cation.
synthetische
4-(6-Methyl-2,3-dihydrobenzo[d]thiazol-2-yl)benzenamine?with methanol and hydrochloric acid or sulfuric acid, at 160 ~ 170 ℃ methylation under pressure.
Allgemeine Beschreibung
Thioflavin T is a benzothiazole dye that increases in fluorescence upon binding to amyloid. Thioflavin T has been used in histology and for protein characterization.
Biochem/physiol Actions
Cell permeable: yes
Lager
Store at -20°C

Properties and Applications

colourful green light yellow. Soluble in cold water, soluble in hot water for yellow, easily soluble in ethanol and yellow, with green fluorescent. The strong sulfuric acid to colorless, a green fluorescent, diluted into light yellow.

Standard( Silk )	Light Fastness	Persperation Fastness		Ironing Fastness		Soaping
Standard( Silk )	Light Fastness	Fading	Stain	Fading	Stain	Fading	Stain
C	3	2-3		4		1

läuterung methode
Crystallise the chloride from *benzene/EtOH (1:1). [Beilstein 27 III/IV 5052.]

Thioflavine T Upstream-Materialien And Downstream Produkte

Thioflavine T Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

2390-54-7, Thioflavine T Verwandte Suche:

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