Natrium-3-hydroxybutyrat

Bezeichnung:Natrium-3-hydroxybutyrat

CAS-Nr150-83-4

Englisch Name:DL-3-Hydroxybutyric acid sodium salt

CBNumberCB6254982

SummenformelC4H7NaO3

Molgewicht126.09

MOL-Datei150-83-4.mol

Synonyma

Natrium-3-hydroxybutyrat

Natrium-3-hydroxybutyrat physikalisch-chemischer Eigenschaften

Schmelzpunkt	167-170 °C
storage temp.	2-8°C
Löslichkeit	Methanol (Slightly, Sonicated), Water (Slightly)
Aggregatzustand	Crystalline Powder
Farbe	White
Sensitive	Hygroscopic
BRN	4824866
Stabilität	Hygroscopic
InChI	InChI=1S/C4H8O3.Na/c1-3(5)2-4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1
InChIKey	NBPUSGBJDWCHKC-UHFFFAOYSA-M
SMILES	C(O)(C)CC([O-])=O.[Na+]
CAS Datenbank	150-83-4(CAS DataBase Reference)

Sicherheit

S-Sätze:	24/25
WGK Germany	3
RTECS-Nr.	205-774-5
F	3-10
HS Code	29181990

Gefahreninformationscode (GHS)

DL-3-Hydroxybutyric acid sodium salt Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
white crystalline powder
Verwenden
DL-3-Hydroxybutyric acid sodium salt has been used in a study to understand the effect of butyrate on fibroblast growth factor 21 (FGF21), which is involved in fatty acid ?-oxidation in liver. It may be used in the preparation of poly(3-hydroxybutyrate).
Verwenden
Optically active 3-hydroxybutyric acids are key intermediates of the biosynthesis and metabolism of fatty acids and exist widely in biological systems.
Definition
ChEBI: An organic sodium salt resulting from the replacement of the proton from the carboxy group of 3-hydroxybutyric acid by a sodium ion.
Application
DL-β-Hydroxybutyric acid sodium salt has been used:
as a standard for quantifying blood plasma and milk β-hydroxybutyric acid in Danish Jersey cows.
to investigate its anticonvulsant effects in epilepsy induced rats.
to induce hyperketonemia in Holstein dairy cows.
Biologische Funktion
Neuroprotective compound in experimental models of neurodegenerative diseases. Shown to be oxidized as an energetic substrate in the brain during starvation. May inhibit brain glucose oxidation, which may account for the suppression of hepatic glucose production observed after administration of ketone bodies in humans.
Biochem/physiol Actions
β-Hydroxybutyric acid is a ketone body present in the rumen epithelium of liver cells. Its interconversion to acetoacetate influences the acid-base balance and is coupled NADH generation from (nicotinamide adenine dinucleotide) NAD+, measured fluorimetrically. A high plasma level of β-hydroxybutyric acid is implicated in diabetic ketoacidosis. It traverses the blood-brain barrier as a monocarboxylic acid. β-Hydroxybutyric acid may play a protective role in dopaminergic neurodegeneration in Parkinson′s disease model. β-Hydroxybutyric acid is a ligand for G protein-coupled receptor(GPR109A) and favors inhibition of secretion, transcription and translation of growth hormone (GH) and prolactin (PRL) gene in cow anterior pituitary cells (DCAPCs).

DL-3-Hydroxybutyric acid sodium salt Upstream-Materialien And Downstream Produkte

Natrium-3-hydroxybutyrat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

150-83-4, DL-3-Hydroxybutyric acid sodium salt Verwandte Suche:

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