Heptafluorbuttersure

Bezeichnung:Heptafluorbuttersure

CAS-Nr375-22-4

Englisch Name:Heptafluorobutyric acid

CBNumberCB5853573

SummenformelC4HF7O2

Molgewicht214.04

MOL-Datei375-22-4.mol

Synonyma

Heptafluorbuttersure

Heptafluorbuttersure physikalisch-chemischer Eigenschaften

Schmelzpunkt	-17.5 °C
Siedepunkt	120 °C755 mm Hg(lit.)
Dichte	1.645 g/mL at 25 °C(lit.)
Dampfdichte	7 (vs air)
Dampfdruck	~10 mm Hg ( 25 °C)
Brechungsindex	n20/D 1.3(lit.)
Flammpunkt	120-121°C
storage temp.	Store below +30°C.
Löslichkeit	Chloroform: soluble; Methanol: soluble
pka	pK1:0.17 (25°C)
Aggregatzustand	Powder
Wichte	approximate 1.6
Farbe	Clear colorless to faint yellow
PH	1 (H2O, 20℃)
Wasserlöslichkeit	miscible
Sensitive	Light Sensitive
BRN	1426882
InChIKey	YPJUNDFVDDCYIH-UHFFFAOYSA-N
CAS Datenbank	375-22-4(CAS DataBase Reference)
NIST chemische Informationen	Butanoic acid, heptafluoro-(375-22-4)
EPA chemische Informationen	Heptafluorobutyric acid (375-22-4)

Sicherheit

Kennzeichnung gefährlicher	C
R-Sätze:	34-35
S-Sätze:	26-36/37/39-45
RIDADR	UN 3265 8/PG 2
WGK Germany	3
RTECS-Nr.	ET4025000
F	3-8-10
Hazard Note	Corrosive
TSCA	T
HazardClass	8
PackingGroup	II
HS Code	29159000

Gefahreninformationscode (GHS)

Heptafluorobutyric acid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R34:Verursacht Verätzungen.
R35:Verursacht schwere Verätzungen.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Chemische Eigenschaften
Clear colorless to faintly yellow liquid
Verwenden
Perfluorobutyric acid was used as mobile phase modifier for enhancement of selectivity in the HPLC analysis of histone proteins. It was used as ion pairing reagent in preparative and analytical reserved phase HPLC of underivatised peptides.
Verwenden
Heptafluorobutyric acid (HBFA) has been used widely for purifying neuropeptides because of its excellent resolution. The use of heptafluorobutyric acid as a volatile ion-pair reagent in the high-performance liquid chromatographic isolation of SB-223070 John K.
Heptafluorobutyric acid is a strong acid and ion-pairing agent that is used in analytical chemistry, notably in HPLC and in gas chromatography/mass spectrometry (GC/MS), in a similar manner to trifluoroacetic acid (TFA). The strong acidity of HFBA ensures that other acidic groups such as carboxylic acid moieties on biomolecules remain protonated, and thus the biomolecule samples are able to interact with organic solvents in such processes as reverse phase chromatography. The longer alkyl chain of HFBA makes it more hydrophobic than TFA, and thus HFBA can be utilized with more hydrophobic samples.
HFBA (0.1%) has been used in the mobile phase of an HPLC/LC-MS protocol for the detection of marine bacterioplankton sideophores.A study of the effects of various acids, including HFBA, on the resolution of intact proteins by reversed-phase LC/ESI-MS has been published.A modified version of the peptide ladder sequencing technique that incorporates allyl isothiocyanate and HFBA has been reported.
Verwenden
Heptafluorobutyric acid is an ion pair reagent for reverse-phase HPLC. It is used in the sequencing, synthesis, and solubilizing of proteins and peptides. It is used as mobile phase modifier for enhancement of selectivity in the HPLC analysis of histone proteins. It is an effective additive for zinc electrodeposition.
Definition
ChEBI: A monocarboxylic acid that is perfluorinated butyric acid.
Allgemeine Beschreibung
Perfluorobutyric acid is an effective additive for zinc electrodeposition.
Hazard
Irritant to tissue.
läuterung methode
Fractionally distil the acid twice in an Oldershaw column (p 10) with an automatic vapour-dividing head, the first distillation being in the presence of conc H2SO4 as a drying agent. (Take care with the hot acid.) [Beilstein 2 IV 810.]

Heptafluorobutyric acid Upstream-Materialien And Downstream Produkte

Heptafluorbuttersure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

375-22-4, Heptafluorobutyric acid Verwandte Suche:

Send Inquriy