Acephat (ISO)

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Sicherheit

  P264：Nach Gebrauch gründlich waschen.

  P264：Nach Gebrauch gründlich waschen.

  P270：Bei Gebrauch nicht essen, trinken oder rauchen.

  P280：Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

  P301+P312：BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.

Acephate Chemische Eigenschaften,Einsatz,Produktion Methoden

• ERSCHEINUNGSBILD

  FARBLOSE KRISTALLEODER WEISSES PULVER MIT CHARAKTERISTISCHEM GERUCH.

• CHEMISCHE GEFAHREN

  Zersetzung beim Erhitzen unter Bildung giftiger Rauche mit Stickstoffoxiden, Phosphoroxidenund Schwefeloxiden.

• ARBEITSPLATZGRENZWERTE

  TLV nicht festgelegt (ACGIH 2005).
  MAK nicht festgelegt (DFG 2005).
  

• AUFNAHMEWEGE

  Aufnahme in den Körper durch Verschlucken und durch Inhalation des Aerosols.

• INHALATIONSGEFAHREN

  Eine gesundheitsschädliche Partikelkonzentration in der Luft kann beim Versprühen oder Dispergieren schnell erreicht werden, vor allem als Pulver.

• WIRKUNGEN BEI KURZZEITEXPOSITION

  WIRKUNGEN BEI KURZZEITEXPOSITION:
  Möglich sind Auswirkungen auf Nervensystem und Blut mit nachfolgender Cholinesterasehemmung. ärztliche Beobachtung notwendig. Die Auswirkungen treten u.U. verzögert ein.

• LECKAGE

  Verschüttetes Material in Behältern sammeln; falls erforderlich durch Anfeuchten Staubentwicklung verhindern. Reste sorgfältig sammeln. An sicheren Ort bringen. NICHT in die Umwelt gelangen lassen. Persönliche Schutzausrüstung: Atemschutzgerät, P2-Filter für schädliche Partikel.

• R-Sätze Betriebsanweisung:

  R22:Gesundheitsschädlich beim Verschlucken.
  R36:Reizt die Augen.
  R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
  R11:Leichtentzündlich.

• S-Sätze Betriebsanweisung:

  S2:Darf nicht in die Hände von Kindern gelangen.
  S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
  S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
  S16:Von Zündquellen fernhalten - Nicht rauchen.

• Beschreibung

  Acephate is an organophosphate foliar spray insecticide of moderate persistence with residual systemic activity. It is a contact and systemic insecticide and very effective against a large number of crop pests such as alfalfa looper, aphids, armyworms, bagworms, bean leaf beetle, bean leafroller, black grass bugs, bollworm, budworm, and cabbage looper. Acephate is a colourless to white solid organophosphate insecticide. Exposures to acephate cause poisoning to animals and humans. Acephate inhibits acetylcholine esterase (AchE), the essential nervous system enzyme, and causes characteristic organophosphate poisoning. The symptoms of toxicity include, but are not limited to, headache, nervousness, blurred vision, weakness, nausea, fatigue, stomach cramps, diarrhoea, difficulty in breathing, chest pain, sweating, pinpoint pupils, tearing, salivation, clear nasal discharge and sputum, vomiting, muscle twitching, muscle weakness, and, in severe poisoning, convulsions, respiratory depression, coma, and death. Acephate causes cholinesterase inhibition leading to overstimulation, respiratory paralysis, and death. The U.S. EPA classified acephate as Group C, meaning a possible human carcinogen, and therefore requires judicious handling and management.

• Chemische Eigenschaften

  Acephate is an organophosphate foliar spray insecticide of moderate persistence with residual systemic activity. It is a contact and systemic insecticide and very effective against a large number of crop pests, such as alfalfa looper, aphids, armyworms, bagworms, bean leafbeetle, bean leafroller, blackgrass bugs, bollworm, budworm, and cabbage looper.

• Chemische Eigenschaften

  Colorless crystalline solid (80% or more pure) or white powder (technical). Has an odor of rotten cabbage or mercaptans (like sulfur).

• Chemische Eigenschaften

  White Solid

• Verwenden

  Acephate is used to control a wide range of sucking and chewing insects in a large number of crops.

• Verwenden

  Contact and systemic insecticide for control of sucking and chewing insects in cotton, ornamentals, forestry, tobacco, fruits, vegetables and other crops

• Verwenden

  Acephate is an organophosphate foliar spray insecticide of moderate persistence with residual systemic activity. It is a contact and systemic insecticide and very effective against a large number of crop pests, such as alfalfa looper, aphids, armyworms, bagworms, bean leafbeetle, bean leafroller, blackgrass bugs, bollworm, budworm, and cabbage looper.

• Definition

  ChEBI: A phosphoramide that is methamidophos in which one of the hydrogens is replaced by an acetyl group.

• Allgemeine Beschreibung

  A white solid. Used as a contact and systemic insecticide.

• Air & Water Reaktionen

  Soluble in water.

• Reaktivität anzeigen

  A thiophosphate ester. Organothiophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

• Health Hazard

  Acephate is a colorless to white, solid organophosphate insecticide. Exposures to acephate cause poisoning to animals and humans. Acephate inhibits acetylcholine esterase (AchE), the essential nervous system enzyme, and causes characteristic organophosphate poi- soning. The symptoms of toxicity include, but are not limited to, headache, nervousness, blurred vision, weakness, nausea, fatigue, stomach cramps, diarrhea, diffi culty breathing, chest pain, sweating, pin-point pupils, tearing, salivation, clear nasal discharge and spu- tum, vomiting, muscle twitching, muscle weakness, and in severe poisonings, convulsions, respiratory depression, coma, and death. Acephate causes cholinesterase inhibition lead- ing to overstimulation, respiratory paralysis, and death.

• Landwirtschaftliche Anwendung

  Insecticide: Acephate is a general use contact and systemic insecticide. Not approved for use in EU countries. Actively registered in the U.S., homeowner use for lawns is discontinued except for treatment of fire ant mounds. Other indoor treatment has been discontinued. Used on green and lima beans, Brussels sprouts, cauliflower, celery, cotton, cottonseed, cranberries, head lettuce, macadamia nuts, peanuts, bell-and non-bell peppers, peppermint, spearmint, tobacco, and soybeans (Special Local Need Registration required in Mississippi and Texas only). Also used to control cockroach (spot treatment only) in residential and industrial buildings and insect control in forests, and on ornamental plants and to target armyworms, aphids, beetles, bollworms, borers, budworms, cankerworms, crickets, cutworms, fire ants, fleas, grasshoppers, leafhoppers, loopers, mealybugs, mites, moths, roaches, spiders, thirps, wasps, weevils, whiteflies, etc.

• Handelsname

  ACECAP SYSTEMIC INSECTICIDE IMPLANTS®; ACEFAL 75 PS®; ACEHERO®; ACEPHATE 97 EG®; ACEPHATE 75SP®; ACEPHATE PCO SP INSECTICIDE®; ACESUL®; ACE-TOX®; ACHERO®; ACIFAT®; ADDRESS®; AIMTHENE®; AMCOTHENE®; ASATAF®; ASIFY®; ATTACK®; CHEVRON RE 12420®; CLEAN CROP ACEPHATE 80 DF SEED PROTECTORANT®; DREXEL ACEPHATE 75 WSP®; DREXEL ACEPHATE PCO SP INSECTICIDE®; FATEL®; FORPHATE®, FORWARD®; KITRON®; KORANDA® (acephate + fenvelerate); LANCER®; ORCEPHATE®; ORTHENE®; ORTHENE 755®; Acephate 3 ORTHO 12420®; ORTRAN®; ORTRIL®; PACE®; PAYLOAD®; PILARTHENE®; PINPOINT®; PRECISE ACEPHATE®; RACET®; RE 12420®; SAPHATE®; 75 SP®; VALENT ORTHENE TECHNICAL®; VEGFRU TARGET®

• Biologische Aktivität

  Anticholinesterase insecticide that produces cholinotoxicity. Displays weak inhibition of rat acetylcholinesterase (AChE) but potently inhibits cockroach AChE.

• Sicherheitsprofil

  Poison by ingestion. Moderately toxic by skin contact and inhalation. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx, POx, and SOx. See also ESTERS.

• mögliche Exposition

  Acephate is a general use contact and systemic insecticide. Banned in the EU for use as a biocide and agricultural insecticide. Used on green- and limabeans, Brussels sprouts, cauliflower, celery, cotton, cottonseed, cranberries, head lettuce, macadamia nuts, peanuts, bell-and nonbell peppers, peppermint, spearmint, tobacco, and soybeans (Special Local Need Registration required in Mississippi and Texas only). Also used to control cockroach (spot treatment only) in residential and industrial buildings and insect control in forests, and on ornamental plants and to target armyworms, aphids, beetles, bollworms, borers, budworms, cankerworms, crickets, cutworms, fire ants, fleas, grasshoppers, leafhoppers, loopers, mealybugs, mites, moths, roaches, spiders, thirps, wasps, weevils, whiteflies, etc. banned for use in the EU.

• Carcinogenicity

  Acephate showed no evidence of carcinogenicity among rats given diets with 0, 5, 50, or 700 ppm (equivalent to about 0, 0.25, 2.5, and 35.0 mg/kg/ day, respectively) for 28 months .

• Environmental Fate

  Soil. In aerobic and anaerobic soils, methamidophos and carbon dioxide were identified as the major soil metabolites (Hartley and Kidd, 1987). The estimated half-life in soil is 3 days (Wauchope, 1988)
  Plant. Acephate is quickly absorbed, translocated and transformed in pine seedlings (Werner, 1974) and cotton plants (Bull, 1979). The chemical was metabolized via cleavage of the amide bond to form methamidophos (O,S-dimethyl phosphoramidothioat
  Chemical/Physical. Emits toxic fumes of phosphorus, nitrogen and sulfur oxides when heated to decomposition (Sax and Lewis, 1987)

• Stoffwechselwegen

  Acephate is a systemic insecticide with a very favourable mammalian toxicity. The initial reaction of the biotransformation of acephate is by hydrolysis to the active acetylcholinesterase inlubitor methamidophos. In every case where the metabolism of acephate has been studied in biological systems, the production of methamidophos has been demonstrated; however, the amount of this presumed active metabolite varies greatly from organism to organism. In mammals, which are relatively insensitive to the insecticide, the primary route of stage I metabolism is mainly degradative via O-demethylation to give des-O-methylacephate. Further metabolism in mammals and birds leads to incorporation of the molecule into proteins, carbohydrates and lipids as well as to excretion. Conjugates have not been identified.

• Versand/Shipping

  UN2783 Organophosphorus pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN3018 Organophosphorus pesticides, liquid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous material

• Degradation

  Acephate is relatively stable to hydrolysis, with DT₅₀s of 60 hours at pH 9 and 710 hours at pH 3 and 40 °C (PM).
  Chukwudebe et al. (1984) studied the breakdown of acephate in 0.1M Tris-HCl buffer at pH 7.2, 8.1 and 8.6 at 37 °C. The hydrolysis products were analysed by GLC with FID for acephate and methamidophos and TLC separation and GLC analysis for the other products. Authenticated standards [methamidophos (2), des-O-methylacephate (3), des-S-methylacephate (4) and O,S-dimethyl phosphorothioate (5)] were used to calibrate the analysis. The major metabolite at all pH values was O,S-dimethyl phosphorothioate (5). This reached a maximum concentration of 40-55% in 1-3 days depending on pH. Its concentration then declined as it was itself hydrolysed. The hydrolysis of acephate was strongly biphasic, with hydrolysis becoming very slow after about 2 days. The amounts of methamidophos (2) (3%) and des-S-methylacephate (4) (10%) produced after 7 days were minor. Major and minor routes for the hydrolysis of methamidophos are shown in Scheme 1.

• Toxicity evaluation

  Although methamidophos is highly toxic to mammals (LD₅₀ mice = 27 mg/kg), the acetylation causes a dramatic decrease in the mammalian toxicity; the acute oral LD₅₀ values of acephate for mice and rats are 361 and 945 mg/kg, respectively. Inhalation LC50 is >15 mg/L air. In 2 years of feeding trials, dogs showed depression of cholinesterase at 100 mg/kg diet (5 mg/kg/d) (maximum dose level). ADI is 0.03 mg/kg.

• Inkompatibilitäten

  May react with strong oxidizers such as chlorates, peroxides, nitrates, etc. In the presence of strong reducing agents such as hydrides, organophosphates form highly toxic and flammable phosphine gas. Contact with oxidizers can cause the release of toxic oxides of phosphorus. Compounds of the carboxyl group react with all bases, both inorganic and organic (i.e., amines) releasing substantial heat, water, and a salt that may be harmful. Incompatible with arsenic compounds(releases hydrogen cyanide gas), diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides (releasing heat, toxic and possibly flammable gases), thiosulfates and dithionites (releasing hydrogen sulfate and oxides of sulfur).

• Waste disposal

  Alkaline hydrolysis or incineration. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Containers must be disposed of properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.

Acephate Upstream-Materialien And Downstream Produkte

Acephat (ISO) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(287)Suppliers

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