Budralazine

Budralazine Chemische Eigenschaften,Einsatz,Produktion Methoden

• R-Sätze Betriebsanweisung:

  R22:Gesundheitsschädlich beim Verschlucken.

• S-Sätze Betriebsanweisung:

  S22:Staub nicht einatmen.
  S24/25:Berührung mit den Augen und der Haut vermeiden.

• Beschreibung

  Budralazine is an antihypertensive agent which is somewhat less potent than structurally related hydralazine, and reportedly produces less tachycardia.

• Originator

  Daiichi (Japan)

• Verwenden

  Budralazine a new antihypertensive agent. Budralazine is a direct-acting vasodilator.

• Definition

  ChEBI: Budralazine is a member of phthalazines.

• Manufacturing Process

  A mixture of 2.0 g of 1-hydrazinophthalazine hydrochloride, 1.1 g of mesityl oxide (isoproplyideneacetone) and 100 ml of ethanol, was refluxed for 3 hours. The reaction mixture was concentrated in vacuo and the residue was dissolved in water. The water solution was neutralized with sodium bicarbonate, salted out and the product was extracted with benzene. The benzene layer was passed through a comparatively short column of alumina and the solvent was removed. The residue was crystallized from ether to give 0.7 g of 1-(1,3-dimethyl-2-butenylidene) hydrazinophthalazine, melting point 131°-132°C.

• Trademarks

  BUTERAZINE

• Therapeutic Function

  Antihypertensive

Budralazine Upstream-Materialien And Downstream Produkte

Budralazine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(60)Suppliers

36798-79-5, Budralazine Verwandte Suche: