D-Glutamine

Bezeichnung:D-Glutamine

CAS-Nr5959-95-5

Englisch Name:D-Glutamine

CBNumberCB3472365

SummenformelC5H10N2O3

Molgewicht146.14

MOL-Datei5959-95-5.mol

D-Glutamine physikalisch-chemischer Eigenschaften

Schmelzpunkt	184-185 °C
Siedepunkt	265.74°C (rough estimate)
alpha	-32 º (589nm, c=10, N HCl)
Dichte	1.3394 (rough estimate)
Brechungsindex	-33 ° (C=5, 5mol/L HCl)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
Löslichkeit	Water (Slightly, Sonicated)
pka	2.27±0.10(Predicted)
Aggregatzustand	Powder
Farbe	White
Wasserlöslichkeit	42.53g/L(temperature not stated)
BRN	1723796
InChIKey	ZDXPYRJPNDTMRX-GSVOUGTGSA-N
LogP	-1.576 (est)
CAS Datenbank	5959-95-5(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	36/37/39-26-27-24/25
WGK Germany	3
HS Code	29241900

Gefahreninformationscode (GHS)

D-Glutamine Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S27:Beschmutzte, getränkte Kleidung sofort ausziehen.
Chemische Eigenschaften
white crystalline powder
Verwenden
D-Glutamine has been used to study its role in conferring protection against acetaldehyde-induced disruption of barrier function in Caco-2 cell monolayer.
Verwenden
D-Glutamine is an unnatural isomer of L-Glutamine (G597000) that is present in human plasma an is a source of liberated ammonia. D-Glutamine can be synthesized by enzymatic means or can be found in cheeses, wine and vinegars as well. It is often used to determine the activity of Glutamine synthetase, an enzyme that is commonly found in the mammalian liver and brain that controls the use of nitrogen in cells.
Definition
ChEBI: The D-enantiomer of glutamine.
Allgemeine Beschreibung
Glutamine is a non-essential and the most abundant free amino acid present in the human body. It is an important component of proteins and is one of the 20 proteinogenic amino acids. It forms 5-6% of bound amino acids.
Biochem/physiol Actions
Glutamine forms the central metabolite in amino acid transamination via a-ketoglutarate and glutamic acid. This amino acid is metabolized by different enzymes, such as glutaminase, present in liver, and glutamine synthetase, present in skeletal muscle. It is produced in the cytoplasm from other amino acids, predominantly from branched-chain amino acids and glutamate. It plays an essential role in ammonia metabolism and detoxification. Its skeletal muscle levels are significantly reduced post trauma, operation and inflammatory states. It servers as a prognostic marker in fatal sepsis during which its skeletal muscle levels are decreased by 90%.

D-Glutamine Upstream-Materialien And Downstream Produkte

D-Glutamine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

5959-95-5, D-Glutamine Verwandte Suche:

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