5959-95-5
基本信息
D-氨羰基丁氨酸
D-麸氨酰胺
D-谷氨酸酰胺
D(-)-GLUTAMIC ACID-5-AMIDE
D-GLUTAMIC ACID 5-AMIDE
D(-)-GLUTAMINE
D-GLUTAMINE
D-GLUTAMINIC ACID 5-AMIDE
H-D-GLN-OH
(R)-2-AMINO-4-CARBAMOYL-BUTYRIC ACID
(2R)-2-amino-4-carbamoyl-butanoic acid
D-Glutamine (9CI)
Glutamine,D-(8Cl)
D-Gln-OH
D-GLUTAMINE extrapure
D-2-Aminoglutaramic acid, D-Glutamic acid 5-amide
Citric Acid, Monohydrate, Crystal, Reagent
物理化学性质
| 外观性质 | 谷氨酰胺的非天然异构体，实际上不溶于甲醇、乙醇、醚和苯。[α]20D -33 ° (c=5, 5 N HCl) |
| 熔点 | 184-185 °C |
| 比旋光度 | -32 º (589nm, c=10, N HCl) |
| 沸点 | 265.74°C (rough estimate) |
| 密度 | 1.3394 (rough estimate) |
| 折射率 | -33 ° (C=5, 5mol/L HCl) |
| 储存条件 | -15°C |
| 溶解度 | 水（轻微，超声处理） |
| 酸度系数(pKa) | 2.27±0.10(Predicted) |
| 形态 | 粉末 |
| 颜色 | 白色 |
| 水溶解性 | 42.53g/L(temperature not stated) |
| BRN | 1723796 |
| InChIKey | ZDXPYRJPNDTMRX-GSVOUGTGSA-N |
| LogP | -1.576 (est) |
| CAS 数据库 | 5959-95-5(CAS DataBase Reference) |
安全数据
| 危险性符号(GHS) |  GHS05 |
| 警示词 | 危险 |
| 危险性描述 | H314 |
| 防范说明 | P501-P264-P280-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P405 |
| 危险品标志 | Xi |
| 危险类别码 | R36/37/38 |
| 安全说明 | S36/37/39-S26 |
| WGK Germany | 3 |
| 海关编码 | 29241990 |
应用领域
知名试剂公司产品信息
D(-)-Glutamine, 98%(5959-95-5) Acros Organics
D-Glutamine,>98.0%(T)(5959-95-5) TCI Shanghai
D-谷氨酰胺价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/11/11 | XW59599553 | D-谷氨酰胺 d-glutamine;2,5-diamino-5-oxopentanoic acid;2-aminoglutaramic acid;glutamic acid 5-amide;h-d-gln-oh | 5959-95-5 | 25G | 582元 |
| 2024/11/11 | XW59599551 | D-谷氨酰胺 d-glutamine;2,5-diamino-5-oxopentanoic acid;2-aminoglutaramic acid;glutamic acid 5-amide;h-d-gln-oh | 5959-95-5 | 1G | 54元 |
| 2024/11/08 | 13516 | D-谷氨酰胺 D(-)-Glutamine, 98% | 5959-95-5 | 1g | 1119元 |
常见问题列表
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Human Endogenous Metabolite
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Glutamine is a key amino acid in the central nervous system (CNS), playing an important role in the glutamate/GABA-Glutamine cycle (GGC). In the GGC,Glutamine is transferred from astrocytes to neurons, where it will replenish the inhibitory and excitatory neurotransmitter pools. D-Glutamine has been used to study its role in conferring protection against acetaldehyde-induced disruption of barrier function in Caco-2 cell monolayer. Role of L-Glutamine in the protection of intestinal epithelium from acetaldehyde-induced disruption of barrier function is evaluated in Caco-2 cell monolayer. L-Glutamine reduced the acetaldehyde-induced decrease in transepithelilal electrical resistance and increase in permeability to inulin and lipopolysaccharide in a time- and dose-dependent manner; D-Glutamine, L-aspargine, L-arginine, L-lysine, or L-alanine produced no significant protection. D-Glutamine also fails to influence the acetaldehyde-induced decrease in TER and increase in inulin flux. D-Glutamine or glutaminase inhibitor by themselves did not influence TER or inulin flux in control or acetaldehyde-treated cell monolayers. Lack of effect of D-Glutamine in protection from acetaldehyde indicates that the L-Glutamine-mediated protection is stereospecific.