Thiaminnitrat

Bezeichnung:Thiaminnitrat

CAS-Nr532-43-4

Englisch Name:Thiamine nitrate

CBNumberCB2472353

SummenformelC12H17N5O4S

Molgewicht327.36

MOL-Datei532-43-4.mol

Synonyma

Thiaminnitrat

Thiaminnitrat physikalisch-chemischer Eigenschaften

Schmelzpunkt	374-392 °C
storage temp.	2-8°C
Löslichkeit	Sparingly soluble in water, freely soluble in boiling water, slightly soluble in alcohol and in methanol.
Aggregatzustand	solid
pka	4.8(at 25℃)
Farbe	White to Off-White
Geruch (Odor)	wh. cryst. or cryst. powd., sl. char. odor
Merck	14,9295
BRN	3857790
Stabilität	Stable. Incompatible with strong oxidizing agents.
InChIKey	UIERGBJEBXXIGO-UHFFFAOYSA-N
CAS Datenbank	532-43-4(CAS DataBase Reference)
EPA chemische Informationen	Thiamine nitrate (532-43-4)

Sicherheit

S-Sätze:	22-24/25
WGK Germany	1
RTECS-Nr.	XI7400000
TSCA	Yes
HS Code	29362200

Thiamine nitrate Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
Thiamine is a water-soluble vitamin with antioxidant, neuroprotective, and anxiolytic properties. It inhibits lipid peroxidation in rat liver microsomes and free radical oxidation of oleic acid in vitro when used at concentrations ranging from 1 to 100 μM. In vivo, thiamine (100 mg/kg) reduces hepatic levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT), lipid peroxidation, and protein damage in a rat model of acute ethanol intoxication. It reverses predator stress-induced suppression of hippocampal neurogenesis and decreases the latency of step-down from a platform, indicating anxiolytic-like activity in mice. Thiamine (8.5 mg/100 g food) reduces neurodegeneration and increases survival in Slc19a3^-/- mice, a model of thiamine metabolism dysfunction syndrome-2 (THMD-2).
Chemische Eigenschaften
White or almost white, crystalline powder or small, colourless crystals.
Verwenden
Vitamin B1.
Verwenden
Thiamine Nitrate is an orally administered vitamin. Thiamine is a essential nutrient required for carbohydrate metabolism and is involved in nerve function.
Allgemeine Beschreibung
Certified pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Thiamine Nitrate is a mononitrate salt of thiamine. It is synthesized from thiamine hydrochloride following a sequence of steps. Thiamine Nitrate is used as a dietary supplement in crackers, eggs substitute and enriched flour.
Sicherheitsprofil
Poison by intravenous and intraperitoneal routes. A powerful oxidizer. When heated to decomposition it emits very toxic fums of SOx, and NOx. See also NITRATES.

Thiamine nitrate Upstream-Materialien And Downstream Produkte

Thiaminnitrat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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