2-Mercaptobenzoxazole

Bezeichnung:2-Mercaptobenzoxazole

CAS-Nr2382-96-9

Englisch Name:2-Mercaptobenzoxazole

CBNumberCB2188290

SummenformelC7H5NOS

Molgewicht151.19

MOL-Datei2382-96-9.mol

2-Mercaptobenzoxazole physikalisch-chemischer Eigenschaften

Schmelzpunkt	192-195 °C(lit.)
Siedepunkt	360°C (rough estimate)
Dichte	1.2170 (rough estimate)
Brechungsindex	1.5500 (estimate)
storage temp.	Sealed in dry,Room Temperature
Aggregatzustand	Crystalline Powder
pka	11.03±0.20(Predicted)
Farbe	Beige
PH	5 (5g/l, H2O, 20℃)
Wasserlöslichkeit	SLIGHTLY SOLUBLE
BRN	119483
InChIKey	FLFWJIBUZQARMD-UHFFFAOYSA-N
CAS Datenbank	2382-96-9(CAS DataBase Reference)
NIST chemische Informationen	2(3H)-Benzoxazolethione(2382-96-9)
EPA chemische Informationen	2-Mercaptobenzoxazole (2382-96-9)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	22-24/25-25-24-36-26
WGK Germany	3
RTECS-Nr.	DM4882500
F	13
TSCA	Yes
HS Code	29349990
Toxizität	mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#04482,

Gefahreninformationscode (GHS)

2-Mercaptobenzoxazole Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S25:Berührung mit den Augen vermeiden.
S24:Berührung mit der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
beige crystalline powder
Verwenden
2-Mercaptobenzoxazole is used in the surface treatment of materials. It is utilized for protection of metals from corrosion.
Definition
ChEBI: 2-mercapto-1,3-benzoxazole is a benzoxazole.
Application
2-Mercaptobenzoxazole is a widely used organic scaffold in medicinal chemistry.
2-Mercaptobenzoxazole and their derivatives are known to posses several biological activities such as antibacterial, antifungal, antiinflammatory, insecticidal and herbicidal. 4-0xo-thiazolidines have also played an important activities as analgesic, anti-HIV, antitubercular, anthelmentic, dye-stuffs, fluorescent and as a photosensitizer. The incorporation of 4-oxothiazolidine and their 5-arylidene moieties in 2-mercaptobenzoxazole frame work has been found to enhance the activity.
synthetische
2-Mercaptobenzoxazole has already been described in 1876 by Dunner (Ber. 9, (1876) page 465). 2-Mercaptobenzoxazole and its derivatives are prepared by processes which are based in principle on the reaction between o-aminophenol and alkali metal alkylxanthates. The alkali metal alkylxanthate here can either be employed as such, or it can be produced in the reaction mixture itself from an alkali, a lower alkanol and carbon disulphide.
https://patents.google.com/patent/US4677209A/en
Reaktionen
2-Mercaptobenzoxazole with ethyl chloroacetate and anhydrous K2C03 in the presence of dry acetone was refluxed on water bath to give ethyl-2-(mercaptobenzoxazolo)acetate.

2-Mercaptobenzoxazole Upstream-Materialien And Downstream Produkte

2-Mercaptobenzoxazole Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

2382-96-9, 2-Mercaptobenzoxazole Verwandte Suche:

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