ISOXAFLUTOLE

Bezeichnung:ISOXAFLUTOLE

CAS-Nr141112-29-0

Englisch Name:ISOXAFLUTOLE

CBNumberCB0382227

SummenformelC15H12F3NO4S

Molgewicht359.32

MOL-Datei141112-29-0.mol

ISOXAFLUTOLE physikalisch-chemischer Eigenschaften

Schmelzpunkt	138-138.5° (Cain); mp 140°
Siedepunkt	575.1±50.0 °C(Predicted)
Dichte	1.59
Flammpunkt	>130 °C
storage temp.	Sealed in dry,2-8°C
Löslichkeit	Chloroform, DCM, Ethyl Acetate, Methanol
pka	-4.29±0.50(Predicted)
Farbe	White
BRN	8344543
LogP	2.320
CAS Datenbank	141112-29-0
EPA chemische Informationen	Isoxaflutole (141112-29-0)

Sicherheit

Kennzeichnung gefährlicher	Xn,N
R-Sätze:	50/53-63
S-Sätze:	36/37-60-61
RIDADR	UN3077 9/PG 3
WGK Germany	3
Giftige Stoffe Daten	141112-29-0(Hazardous Substances Data)
Toxizität	LD50 in rats, quails, mallard ducks (mg/kg): >5000, >2150, >2150 orally; in rabbits (mg/kg): >2000 dermally (Luscombe)

Gefahreninformationscode (GHS)

ISOXAFLUTOLE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R50/53:Sehr giftig für Wasserorganismen, kann in Gewässern längerfristig schädliche Wirkungen haben.
R63:Kann das Kind im Mutterleib möglicherweise schädigen.
S-Sätze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S60:Dieses Produkt und sein Behälter sind als gefährlicher Abfall zu entsorgen.
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
Beschreibung
Isoxaflutole is a 4-benzoyl isoxazole molecule and is used as a pre- and early post-emergence herbicide for the control of a wide range of important broadleaf and grass weeds in maize (Zea mays), both in Europe and in North America. It is also registered for use in sugarcane in Central and South America (2–4). It causes characteristic bleaching of newly developed tissues of susceptible species followed by growth cessation and necrosis. Marketed as Balance for corn (maize) in the United States, and Merlin for corn in Europe; and in sugarcane, it mixes well with metolachlor, acetochlor, dimethenamid, and atrazine to complete the weed spectrum and to reduce the application rates of the latter compounds (2). Isoxaflutole also controls triazineresistant weeds in the field (4).
Verwenden
Isoxaflutole is an pesticide used to selectively control both grass and broad-leaved weeds in maize and sugar cane. Isoxaflutole is known to work by inhibiting the enzyme 4-Hydroxyphenylpyruvate dioxygenase (HPPD) which results in the disruption of pigment biosynthesis.
Verwenden
Herbicide.
Definition
ChEBI: Isoxaflutole is a member of the class of isoxazoles that is 1,2-oxazole substituted by a 2-(methanesulfonyl)-4-(trifluoromethyl)benzoyl group and a cyclopropyl group at positions 4 and 5, respectively. It is a 4-hydroxyphenylpyruvate dioxygenase inhibitor which is used as a herbicide for weed control in maize and sugarcane. It has a role as an EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor, a proherbicide and an agrochemical. It is a member of cyclopropanes, a member of isoxazoles, an aromatic ketone, a member of (trifluoromethyl)benzenes and a sulfone.
Pharmakologie
Isoxaflutole is readily taken up by roots and foliar tissues and then rapidly degraded to a diketonitrile derivative (2-cyclopropyl-3-(2-mesyl-4-trifluoromethylphenyl)- 3-oxo propanenitrile) , which is translocated throughout the plant via xylem and phloem (2,3,6,8). It is this metabolite that inhibits HPPD (7), thereby depleting the plastoquinone pools in developing leaves. Plastoquinone is a cofactor in the desaturation of phytoene, levels of which increase in bleached leaves, concomitant with decreases in colored carotenoids (6). Although bleaching is the primary symptom associated with HPPD inhibition, subsequent growth suppression and necrosis are also believed to be a consequence (8).
Isoxaflutole also degrades to the diketonitrile derivative in the soil (3,8). The half-life of isoxaflutole in soil is dependent on soil type, pH, and moisture, ranging from 12 hours to 3 days under laboratory conditions (8). The physicochemical properties of isoxaflutole and of diketonitrile play an important role in both soil and herbicidal activity and selectivity (8).

ISOXAFLUTOLE Upstream-Materialien And Downstream Produkte

ISOXAFLUTOLE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

141112-29-0, ISOXAFLUTOLE Verwandte Suche:

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