Isoxazole Struktur

Isoxazol

Bezeichnung:Isoxazol

CAS-Nr288-14-2

Englisch Name:Isoxazole

CBNumberCB3485864

SummenformelC3H3NO

Molgewicht69.06

MOL-Datei288-14-2.mol

Synonyma

Isoxazol

Isoxazol physikalisch-chemischer Eigenschaften

Schmelzpunkt	-67.1°C
Siedepunkt	93-95 °C(lit.)
Dichte	1.078 g/mL at 25 °C(lit.)
Dampfdichte	2.4 (vs air)
Brechungsindex	n20/D 1.427(lit.)
Flammpunkt	48 °F
storage temp.	2-8°C
Löslichkeit	167g/l
pka	-2.0(at 25℃)
Aggregatzustand	clear liquid
Farbe	Colorless to Light yellow
BRN	103773
Henry's Law Constant	4.0×10^-1 mol/(m³Pa) at 25℃, Duchowicz et al. (2020)
InChI	1S/C3H3NO/c1-2-4-5-3-1/h1-3H
InChIKey	CTAPFRYPJLPFDF-UHFFFAOYSA-N
SMILES	c1cnoc1
CAS Datenbank	288-14-2(CAS DataBase Reference)
NIST chemische Informationen	Isoxazole(288-14-2)
EPA chemische Informationen	Isoxazole (288-14-2)

Sicherheit

Kennzeichnung gefährlicher	F,Xi
R-Sätze:	11
S-Sätze:	16-23/33-33-29-7/9
RIDADR	UN 1993 3/PG 2
WGK Germany	3
F	10
Hazard Note	Highly Flammable
TSCA	TSCA listed
HazardClass	3
PackingGroup	II
HS Code	29349990
Speicherklasse	3 - Flammable liquids
Hazard Classifications	Flam. Liq. 2

Gefahreninformationscode (GHS)

Isoxazole Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R11:Leichtentzündlich.
S-Sätze Betriebsanweisung:
S16:Von Zündquellen fernhalten - Nicht rauchen.
S33:Maßnahmen gegen elektrostatische Aufladungen treffen.
S29:Nicht in die Kanalisation gelangen lassen.
S7/9:Behälter dicht geschlossen an einem gut gelüfteten Ort aufbewahren.
Beschreibung
Isoxazole, an important class of heterocycles, is a five membered heterocyclic compound that exhibits various pharmacological actions. It is present in some natural products such as ibotenic acid and is also used as a foundation for several drugs such as the COX-2 inhibitor valdecoxib and anti-inflammatory drugs. Isoxazoles are largely applied in the area of pharmaceuticals and therapeutics, including insecticidal, antibacterial, antibiotic, antitumour, antifungal, antituberculosis, anticancer and ulcerogenic. Besides, it has a great effect on reducing blood glucose, eliminating pain, resisting inflammation, killing harmful bacteria, controlling and reducing the risk of HIV.
Chemische Eigenschaften
A colorless liquid resembling pyridine. It is soluble in water at room temperature up to six times its volume.
Verwenden
Natural insecticide.
Definition
ChEBI: Isoxazole is a monocyclic heteroarene with a structure consisting of a 5-membered ring containing three carbon atoms and an oxygen and nitrogen atom adjacent to each other. It is the parent of the class of isoxazoles. It is a mancude organic heteromonocyclic parent, a monocyclic heteroarene and a member of isoxazoles.
synthetische
Isoxazoles can be synthesized by various methods, such as the 1,3-dipolar cycloaddition reaction of nitrile oxides with alkynes, the reaction of hydroxylamine with 1,3-diketones or propiolic acid derivatives, etc.
www.organic-chemistry.org
Allgemeine Beschreibung
Isoxazole(288-14-2) are described as inhibitors of acetylcholinesterase (AChE). Isoxazole ligands bind to and inhibit the Sxc- antiporter.
Hazard
Narcotic and psychomimetic effects.
Einzelnachweise
https://en.wikipedia.org/wiki/Isoxazole
https://pubchem.ncbi.nlm.nih.gov/compound/9254

Isoxazole Upstream-Materialien And Downstream Produkte

Isoxazol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

288-14-2, Isoxazole Verwandte Suche:

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