Chlorproethazin

chlorproethazine Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

  Off-White Solid

• Originator

  Neuriplege, Genevrier ,France,1961

• Verwenden

  MIchlorproethazine.

• Definition

  ChEBI: Chlorproethazine is a member of phenothiazines.

• Manufacturing Process

  2-Bromo-2'-(3''-dimethylaminopropyl)-amino-4'-chlorodiphenylsulfide (10 g) is dissolved in dimethylformamide (80 cc). To this solution is added potassium carbonate (5 g) and copper powder (0.4 g). It is then heated under reflux for 48 hours, cooled, and the insoluble matter filtered off. After washing with dimethylformamide (20 cc), the filtrate is taken up in distilled water (200cc). The base formed is extracted with ether (3 times with 50 cc), the ethereal solution is dried over sodium sulfate, the ether driven off on a water-bath and the residue distilled. In this way there is obtained 3-chloro-10-(3'- dimethylaminopropyl)-phenothiazine (6.4 g) which boils at 210 C to 225°C under 0.7 mm of mercury. The hydrochloride is made by the action of ethereal hydrogen chloride on the base dissolved in acetone; this hydrochloride melts at 180°C

• Therapeutic Function

  Muscle relaxant; Tranquilizer

chlorproethazine Upstream-Materialien And Downstream Produkte

Chlorproethazin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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