Tetracyclinhydrochlorid Produkt Beschreibung

Tetracycline hydrochloride Struktur
64-75-5
  • CAS-Nr.64-75-5
  • Bezeichnung:Tetracyclinhydrochlorid
  • Englisch Name:Tetracycline hydrochloride
  • Synonyma:Tetracyclinhydrochlorid
    alatet;paltet;qidtet;teline;tet-cy;u-5965;unicin;partrex;quatrex;sumycin
  • CBNumber:CB1704886
  • Summenformel:C22H25ClN2O8
  • Molgewicht:480.9
  • MOL-Datei:64-75-5.mol
Tetracyclinhydrochlorid physikalisch-chemischer Eigenschaften
  • Schmelzpunkt: :220-223 °C(lit.)
  • alpha  :-252 º (c=0.5, H2O)
  • Brechungsindex :-253 ° (C=0.5, 0.1mol/L HCl)
  • storage temp.  :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
  • Löslichkeit :H2O: 10 mg/mL as a stock solution. Stock solutions should be filtered sterilized and stored at −20°C. Stable at 37°C for 4 days.
  • Aggregatzustand :powder
  • Farbe :faint yellow to yellow
  • PH :pH(10g/l, 25℃) : 1.8~3.0
  • Optische Aktivität :[α]/D -255 to 240° (Specific rotation )
  • Wasserlöslichkeit :50 g/L
  • Sensitive  :Air & Light Sensitive
  • Merck  :14,9196
  • BRN  :3844873
  • Stabilität: :Stable. Incompatible with strong oxidizing agents.
  • InChIKey :XMEVHPAGJVLHIG-FMZCEJRJSA-N
  • CAS Datenbank :64-75-5(CAS DataBase Reference)
  • EPA chemische Informationen :Tetracycline hydrochloride (64-75-5)
Sicherheit
  • Kennzeichnung gefährlicher :Xi,Xn
  • R-Sätze: :36/37/38-20/21/22
  • S-Sätze: :26-36
  • RIDADR  :UN 3077 9 / PGIII
  • WGK Germany  :2
  • RTECS-Nr. :QI9100000
  • F  :8-10-23
  • TSCA  :Yes
  • HazardClass  :3
  • HS Code  :29413000
  • Toxizität :LD50 orally in rats: 6443 mg/kg (Goldenthal)

Tetracycline hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

  • R-Sätze Betriebsanweisung: R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
    R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
  • S-Sätze Betriebsanweisung: S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
    S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
  • Chemische Eigenschaften Yellow crystalline powder
  • Verwenden Antibiotic substance produced by Streptomyces spp. Antiamebic; antibacterial; antirickettsial.
  • Verwenden Tetracycline hydrochloride is a salt prepared from tetracycline taking advantage of the basic dimethylamino group which protonates and readily forms the salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Tetracycline hydrochloride has broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-unit,s blocking protein synthesis.
  • Allgemeine Beschreibung Crystals or fine bright yellow powder. pH of 2% aqueous solution: 2.1 - 2.3.
  • Air & Water Reaktionen Water soluble.
  • Reaktivität anzeigen Tetracycline hydrochloride is acidic. Reacts with strong oxidizing agents .
  • Brandgefahr Flash point data concerning Tetracycline hydrochloride are not available, however, Tetracycline hydrochloride is probably combustible.
  • Sicherheitsprofil Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Human systemic effects: change in taste function. An experimental teratogen. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of HCl and NOx. See also TETRACYCLINE.
  • Veterinary Drugs and Treatments While tetracycline still is used as an antimicrobial, most small animal clinicians prefer doxycycline and large animal clinicians prefer oxytetracycline when a tetracycline is indicated to treat susceptible infections. The most common use of tetracycline HCl today is in combination with niacinamide for the treatment of certain immune- mediated skin conditions in dogs, such as pemphigus.
  • läuterung methode The hydrochloride is recrystallised from MeOH/n-BuOH or n-BuOH/HCl. It is insoluble in Et2O and pet ether. It has UV max at 270 and 366nm in MeOH. [Gottstein et al. J Am Chem Soc 81 1198 1959, Conover et al. J Am Chem Soc 84 3222 1962, Stephen et al. J Am Chem Soc 78 4155 1956, Beilstein 14 IV 2627.]
Tetracycline hydrochloride Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Tetracyclinhydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
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64-75-5, Tetracycline hydrochloride Verwandte Suche:
  • alatet
  • amycin,hydrochloride
  • artomycin
  • cancycline-250
  • cefracyclinetablets
  • chlorhydratedetetracycline
  • chlorowodorkutetracykliny
  • cyclopar
  • diacycine
  • dumocyclin
  • hostacycline
  • medamycin
  • mephacyclin
  • nci-c55561
  • neocyclineb
  • paltet
  • panmycinhydrochloride
  • partrex
  • piracaps
  • polycyclinehydrochloride
  • polyoticointment
  • qidtet
  • quadracycline
  • quatrex
  • remicyclin
  • ricycline
  • ro-cycline
  • sanclomycine
  • stilciclina
  • subamycin
  • sumycin
  • supramycin
  • tefilin
  • teline
  • telotrex
  • tet-cy
  • tetrabakat
  • tetrabid
  • tetrablet
  • tetracaps
  • tetrachel
  • tetraciclinacloridrato
  • tetracompren
  • tetracyclinechlorohydrate
  • Tetracylinehydrochloride
  • tetra-d
  • tetrakap
  • tetralution
  • tetramavan
  • tetra-wedel
  • tetrosol
  • topicycline
  • triphacyclin
  • u-5965
  • unicin
  • unimycin
  • vetquamycin-324
  • TETRACYCLIN HYDROCHLORIDE VETRANAL, 250 MG