3-Hydroxy-3-methyl-2-butanone

Bezeichnung:3-Hydroxy-3-methyl-2-butanone

CAS-Nr115-22-0

Englisch Name:3-Hydroxy-3-methyl-2-butanone

CBNumberCB0367448

SummenformelC5H10O2

Molgewicht102.13

MOL-Datei115-22-0.mol

3-Hydroxy-3-methyl-2-butanone physikalisch-chemischer Eigenschaften

Schmelzpunkt	84-85 °C
Siedepunkt	140-141 °C (lit.)
Dichte	0.971 g/mL at 25 °C (lit.)
Brechungsindex	n20/D 1.415(lit.)
Flammpunkt	108 °F
storage temp.	Flammables area
Löslichkeit	Soluble in chloroform.
pka	13.28±0.29(Predicted)
Aggregatzustand	Liquid
Farbe	Clear colorless to yellow or light red
BRN	1616385
InChI	1S/C5H10O2/c1-4(6)5(2,3)7/h7H,1-3H3
InChIKey	BNDRWEVUODOUDW-UHFFFAOYSA-N
SMILES	CC(=O)C(C)(C)O
LogP	0.112 (est)
CAS Datenbank	115-22-0(CAS DataBase Reference)
EPA chemische Informationen	2-Butanone, 3-hydroxy-3-methyl- (115-22-0)

Sicherheit

R-Sätze:	10
S-Sätze:	23-24/25-22
RIDADR	UN 1224 3/PG 3
WGK Germany	3
TSCA	TSCA listed
HazardClass	3
PackingGroup	III
HS Code	29144000
Speicherklasse	3 - Flammable liquids
Hazard Classifications	Flam. Liq. 3

Gefahreninformationscode (GHS)

3-Hydroxy-3-methyl-2-butanone Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R10:Entzündlich.
S-Sätze Betriebsanweisung:
S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S24/25:Berührung mit den Augen und der Haut vermeiden.
S22:Staub nicht einatmen.
Chemische Eigenschaften
CLEAR COLOURLESS TO LIGHT YELLOW LIQUID
Verwenden
3-Hydroxy-3-methyl-2-butanone used to produce 2,5-dihydroxy-2-methyl-heptan-3-one, laboratory chemicals.
Application
3-Hydroxy-3-methyl-2-butanone is an alpha-hydroxy ketone compound. It can be used as a biologically active natural product and a pharmaceutical intermediate, and as a photoinitiator in UV-curable coatings. At the same time, α-hydroxyketone structural units are also widely used synthons in organic synthesis. Hydroxyl can be used as a mild reaction precursor for double bonds, ester groups, carbonyl groups, halogenated hydrocarbons and other groups. Carbonyl can be used as the reaction precursor of hydroxyl, amino, alkyl and other groups. Therefore, α-hydroxyketone compounds are a class of compounds with important application value.
synthetische
synthesis of 3-Hydroxy-3-methyl-2-butanone: 19ml of concentrated sulfuric acid (98wt%) was slowly mixed with 100ml of water, then 13g of yellow mercury oxide was added within 1.5h, 84g (1.0mol) of 2-methyl-3-butyn-2-ol was added dropwise to the sulfuric acid solution containing mercury oxide at 65-75°C, Then the reaction was stirred at 65-75°C for 30min, cooled to room temperature after the reaction was completed, the reaction product was subjected to suction filtration, the filtrate after suction filtration was extracted with ether (3×20ml), and the organic phase after extraction was water and hydrogen carbonate respectively. Washed with sodium solution, the washed organic phase was dried with anhydrous magnesium sulfate, and then filtered, the filtered filtrate was concentrated by rotary evaporation and then distilled, and the 140°C fraction was collected, 45.6 g of light yellow liquid was obtained as 3-hydroxy-3-methyl-2-butanone, and the yield was 32.2%.
Definition
ChEBI: 3-Hydroxy-3-methylbutan-2-one is a secondary alpha-hydroxy ketone.

3-Hydroxy-3-methyl-2-butanone Upstream-Materialien And Downstream Produkte

3-Hydroxy-3-methyl-2-butanone Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

115-22-0, 3-Hydroxy-3-methyl-2-butanone Verwandte Suche:

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