6153-64-6
基本信息
4-二甲氨基-1,4,4a,5,5a,6,11,12a-八氢-3,5,6,10,12,12a-六羟基-6-甲基-1,11-二氧代-并四苯-2-甲酰胺二水合物
6-甲基-4-(二甲氨基)-3,5,10,12,12a-五羟基-1,11-二氧代-1,4,4a,5,5a,6,11,12a-八氢-2-并四苯甲酰胺
地霉素
多西环素
强力霉素
土霉素
土霉素注射液
脱氧土霉素
氧四环素
氧四环素/土霉素 二水合物
二水合土霉素
地霉素
强力霉素
土霉素二水合物
5-hydroxytetracycline
OXYTETRACYCLINE DIHYDRATE
terramycin
OXYCYCLINE
DOXYCYCLINE USP 23
OXYTETRACYCLINE HCL BP
DOXYCYCLINE HYDRATE BP98 USP23
DOXYCYCLINE HYCHLATE
DOXYCYCLINE HCL ( VETERINARY)
trramycin
OXYTETRACYCLINE DIHYDRATE SIGMAULTRA
OxytetracyclineHcl2058-46-0,
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, dihydrate, (4S,4aR,5S,5aR,6S,12aS)-
OXYTETRACYCLINEFEED
OXYTETRACYCLINE DIHYDRATE, INJECTABLE GRADE
OXYTETRACYCLINE DIHYDRATE, ORAL GRADE
4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide dihydrate
物理化学性质
| 熔点 | 181-182 °C |
| 比旋光度 | -216 º (c=1,0.1 M HCl) |
| 储存条件 | 0-6°C |
| 溶解度 | 1 M HCl: 0.1 M yellow to yellow-orange, clear |
| 形态 | crystalline |
| 形态 | crystalline |
| 颜色 | yellow |
| 颜色 | 黄色 |
| 水溶解性 | 微溶 |
| CAS 数据库 | 6153-64-6(CAS DataBase Reference) |
| EPA化学物质信息 | Oxytetracycline dihydrate (6153-64-6) |
安全数据
| 危险性符号(GHS) |   GHS08,GHS09 |
| 警示词 | 警告 |
| 危险性描述 | H361d-H411 |
| 防范说明 | P201-P202-P273-P280-P308+P313-P391 |
| 危险品标志 | Xn |
| 危险类别码 | R63-R36 |
| 安全说明 | S22-S24/25-S36/37/39-S26 |
| WGK Germany | 3 |
| 海关编码 | 29413020 |
应用领域
知名试剂公司产品信息
Oxytetracycline dihydrate, 95%(6153-64-6) Acros Organics
常见问题列表
|
HSV-1
|
Bacterial
|
Human Endogenous Metabolite
|
Oxytetracycline is an important member of the bacterial aromatic polyketide family, which is a structurally diverse class of natural products. Oxytetracycline is synthesized by a type II polyketide synthase that generates the poly-beta-ketone backbone through successive decarboxylative condensation of malonyl-CoA extender units, followed by modifications by cyclases, oxygenases, transferases, and additional tailoring enzymes.
The effects of administration a therapeutic dose of Oxytetracycline (82.8 mg/kg of bw to 1 % bw/day) for 10 days are species specific. Oxytetracycline increases the relative liver weight in
Morone chrysops x M. saxatilis
, the enzymatic activity of CYP3A4 in Ictalurus punctatus, protein expression of CYP3A4 in Oreochromis niloticus and depleted the hepatic CYP3A4 in the latter.
For Oxytetracycline, the limits are 100 μg/kg in muscle and milk, 200 μg/kg in egg, 300 μg/kg in liver and 600 μg/kg in kidney. Oxytetracycline (OTC) is administered to fish as medicated feed at concentrations ranging from 35 to 75 mg a.i kg-1 biomass day-1 for 7-14 days.