2011-67-8
中文名称
硝甲西泮
英文名称
Nimetazepam
CAS
2011-67-8
EINECS 编号
217-931-5
分子式
C16H13N3O3
MDL 编号
MFCD00242916
分子量
295.29
MOL 文件
2011-67-8.mol
结构式
基本信息
中文别名
1,3-二氢-1-甲基-7-硝基-5-苯基-2H-1,4-苯并二氮杂卓-2-酮
甲硝西泮
尼美西泮
硝甲西泮
甲硝西泮
尼美西泮
硝甲西泮
英文别名
1,3-dihydro-1-methyl-7-nitro-5-phenyl-2h-1,4-benzodiazepin-2-one
1-methyl-7-nitro-5-phenyl-1h-1,4-benzodiazepin-2(3h)-one
NIMETAZEPAM
1,3-dihydro-1-methyl-7-nitro-5-phenyl-2h-4-benzodiazepin-2-one
1-Methyl-5-phenyl-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one
1-Methyl-7-nitro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
1-Methylnitrazepam
2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-1-methyl-7-nitro-5-phenyl-
Elimin
Hypnon
Nimetazam
Nitrazepam, methylated
ro5-3453
S 1530
N-Methylmogadon
1-methyl-7-nitro-5-phenyl-1h-1,4-benzodiazepin-2(3h)-one
NIMETAZEPAM
1,3-dihydro-1-methyl-7-nitro-5-phenyl-2h-4-benzodiazepin-2-one
1-Methyl-5-phenyl-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one
1-Methyl-7-nitro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
1-Methylnitrazepam
2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-1-methyl-7-nitro-5-phenyl-
Elimin
Hypnon
Nimetazam
Nitrazepam, methylated
ro5-3453
S 1530
N-Methylmogadon
所属类别
原料药：其它神经系统用药
物理化学性质
| 熔点 | 156.5-157.5° |
| 沸点 | 436.98°C (rough estimate) |
| 密度 | 1.1952 (rough estimate) |
| 折射率 | 1.6500 (estimate) |
| 闪点 | 9℃ |
| 储存条件 | -20°C |
| 溶解度 | 可溶于氯仿（少许）、甲醇（少许） |
| 酸度系数(pKa) | pKa 2.53(EtOH/H2O,t =25,Iundefined) (Uncertain) |
| 形态 | 固体 |
| 颜色 | 淡黄色至深黄色 |
| CAS 数据库 | 2011-67-8(CAS DataBase Reference) |
| NIST化学物质信息 | Nimetazepam(2011-67-8) |
安全数据
| 危险性符号(GHS) |    GHS02,GHS06,GHS08 |
| 警示词 | 危险 |
| 危险性描述 | H225-H301+H311+H331-H370 |
| 防范说明 | P210-P260-P280-P301+P310-P311 |
| 危险品标志 | F,T |
| 危险类别码 | 11-23/24/25-39/23/24/25 |
| 安全说明 | 16-36/37-45 |
| 危险品运输编号 | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK Germany | 1 |
| 毒性 | LD50 in male, female mice, rats (mg/kg): 910, 750, 1150, 970 orally; 970, 840, 970, 980 i.p.; 1500, 1500, 1000, 1000 s.c. (Sakai) |
| DEA Controlled Substances | CSCN: 2837 CSA SCH: Schedule IV NARC: No |
应用领域
用途一
抗精神病药。