146-14-5
基本信息
氟-氨碇
腺嘌呤黄素
黄素腺嘌呤二核苷酸
核黄素腺苷双核苷酸
二核苷酸黄素腺嘌呤
二核苷酸核黄素腺苷
腺嘌呤黄素二核苷酸
腺[嘌呤]黃素二苷酸
Β-黄素腺嘌呤二核苷酸
flavinat
flavitan
Flavinin
Wakadenin
NSC 112207
Flavine Adenine
5'-ester with adenosine
flavinadenindinucleotide
adenine-flavindinucleotide
物理化学性质
| 外观性状 | 橙黄色粉末，有吸湿性，易溶于水，不溶于乙醇，水溶液呈黄绿色荧光，遇碱分解为核黄素。 |
| 密度 | 2.08±0.1 g/cm3(Predicted) |
| 储存条件 | −20°C |
| 溶解度 | 可溶于甲醇（轻微加热）、水（轻微） |
| 酸度系数(pKa) | 1.13±0.50(Predicted) |
| 形态 | powder |
| 颜色 | orange |
| Merck | 4091 |
| 稳定性 | 稳定的。与强氧化剂不相容。 |
| InChIKey | VWWQXMAJTJZDQX-ZGGJIJKNNA-N |
| CAS 数据库 | 146-14-5 |
| EPA化学物质信息 | Riboflavin 5'-(trihydrogen diphosphate), P'.fwdarw.5'-ester with adenosine (146-14-5) |
安全数据
| 危险性符号(GHS) |  GHS07 |
| 警示词 | 警告 |
| 危险性描述 | H315-H319-H335 |
| 防范说明 | P280-P302+P352-P362+P364 |
| 安全说明 | 24/25 |
| WGK Germany | 3 |
| RTECS号 | AU7470000 |
| F | 8-10-21 |
| 海关编码 | 29349990 |
应用领域
常见问题列表
黄素腺嘌呤二核苷酸（英语：FAD），又称活性型维生素B2、核黄素-5'-腺苷二磷酸，是一种参与了重要的代谢反应的氧化还原辅酶。FAD是一种比NAD和NADP更强的氧化剂，能被1个电子或2个电子途径还原。其可用于标记黄嘌呤腺嘌呤氧化酶，核黄素激酶肿瘤坏死因子受体1 NADPH氧化酶。
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Human Endogenous Metabolite
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Poly(Flavin adenine dinucleotide, FAD) characterized by an additional polymer-type redox reaction is a highly effective electrocatalyst for NADH oxidation: operating at the lowest potentials reported for NADH transducers (0.00 V, pH 7.4), poly(FAD) is characterized by the electrochemical rate constant of 1.8 ± 0.6×10 -3 cm/s, which is at the level of the NADH mass-transfer constant. Poly(FAD)-modified electrodes are characterized by the dramatically improved stability and, is the most advantageous NADH transducers for analytical chemistry.
Flavin adenine dinucleotide (2 mg/kg, i.v.) significantly cancels chlorpromazine (CPZ)-induced decrease in ventricular fibrillation threshold (VFT). Flavin adenine dinucleotide cancels the effect of CPZ on canine heart mitochondria. After injection of Flavin adenine dinucleotide, the dogs show a transient hypotension within 10 min, then their blood pressures recover to the initial level. Flavin adenine dinucleotide also prevents mitochondrial dysfunction induced by chlorpromazine.
黄素腺嘌呤二核苷酸价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/02/08 | HY-B1654 | 黄素腺嘌呤二核苷酸 Flavin adenine dinucleotide | 146-14-5 | 1 mg | 231元 |
| 2025/02/08 | HY-B1654 | 黄素腺嘌呤二核苷酸 Flavin adenine dinucleotide | 146-14-5 | 5 mg | 500元 |
| 2025/02/08 | HY-B1654 | 黄素腺嘌呤二核苷酸 Flavin adenine dinucleotide | 146-14-5 | 10 mM * 1 mLin Water | 648元 |