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Trinexapac-ethyl is a synthetic plant growth regulator developed by Syngenta, Switzerland. It inhibits the production of gibberellic acid and shortens the internodes on grasses grown for seed and cereals which results in a reduction in lodging. It can be used for crop height reduction, lodging prevention and yield protection in all varieties of winter and spring wheat, winter and spring barley and winter and spring oats, durum wheat, rye, triticale and grassland (seed crops).

Plant growth regulator.

ChEBI: A member of the class of cyclohexanones that is ethyl 3,5-dioxocyclohexanecarboxylate substituted by a cyclopropyl(hydroxy)methylidene group at position 4.

The U.S. EPA has classified trinexapac-ethyl as "not likely to be carcinogenic to humans."
No studies area available in humans to inform on carcinogenicity of trinexapac-ethyl.
The carcinogenic potential of trinexapac-ethyl has been well investigated in two guideline and GLP compliant dietary studies; a 2-year study in the Sprague-Dawley rat (Anon., 1992) and an 18-month study in the CD-1 mouse (Anon., 1991).
Overall, RAC agreed with the DS that there is insufficient evidence to support classification for carcinogenicity.

Trinexapac-ethyl acts as an inhibitor of the action of a key enzyme in the formation of gibberellic acid (GA1), preventing the formation of the plant growth regulator gibberellins, which promotes cell elongation. In the absence of gibberellins the internodes of the plants fail to grow and prevent the plant from growing taller.  This can be used to prevent lodging in crops and amenity turf, increase the yield in crops by redirecting energy into the production of reproductive parts and finally to reduce the frequency of mowing in turf.