General Description
Yellow needles. Free soluble in alcohol.
Reactivity Profile
9-AMINOACRIDINE(90-45-9) is a moderately strong base. Neutralizes acids to form salts plus water in exothermic reactions. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides.
Air & Water Reactions
Insoluble in water.
Fire Hazard
Flash point data for this chemical are not available; however, 9-AMINOACRIDINE is probably combustible.
Chemical Properties
yellow crystals or powder
Uses
Acridine analog. DNA intercalating agent.
Definition
ChEBI: An aminoacridine that is acridine in which the hydrogen at position 9 is replaced by an amino group. A fluorescent dyd and topical antiseptic agent, it is used (usually as the hydrochloride salt) in eye drops for the treatment of superficial eye infections
Brand name
Monacrin
(Sterling Winthrop).
Purification Methods
It crystallises from EtOH or acetone and sublimes at 170-180o/0.04mm [Albert & Ritchie Org Synth Coll Vol III 53 1955, for hydrochloride, see below]. [Beilstein 22 H 463, 21 II 280, 21 III/IV 4174.]
