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87333-19-5

Name Ramipril
CAS 87333-19-5
EINECS(EC#) 642-904-3
Molecular Formula C23H32N2O5
MDL Number MFCD00865775
Molecular Weight 416.51
MOL File 87333-19-5.mol

Chemical Properties

Appearance White Solid
Melting point  106-108°C
alpha  D24 +33.2° (c = 1 in 0.1N ethanolic HCl)
Boiling point  616.2±55.0 °C(Predicted)
density  1.200±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  DMSO: ~18mg/mL
form  powder
pka pKa 3.30±0.01(H2O t = 25.0 I = 0.15 (KCl)) (Uncertain);5.75±0.00(H2O t = 25.0 I = 0.15 (KCl)) (Uncertain)
color  white
Usage An antihypertensive. An angiotensin converting enzyme (ACE) inhibitor, converted to active, diacid metabolite
BCS Class 1
CAS DataBase Reference 87333-19-5(CAS DataBase Reference)

Safety Data

Hazard Codes  Xi
Risk Statements 
R36/38:Irritating to eyes and skin .
Safety Statements 
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
WGK Germany  2
RTECS  GY5879600
HS Code  2933995300
Hazardous Substances Data 87333-19-5(Hazardous Substances Data)
Toxicity
LD50 (14 day) in male, female mice, male, female rats (mg/kg): 1194, 1158, 687, 608 i.v.; 10933, 10048, >10000, >10000 orally (Donaubauer, Mayer)

Hazard Information

Material Safety Data Sheet(MSDS)

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