873-63-2

CLEAR COLOURLESS LIQUID

3-Chlorobenzyl alcohol serves as a model benzene derivative for investigating electronic structural impacts[3].

ChEBI: (3-Chlorophenyl)methanol is a member of benzyl alcohols.

Chemistry Letters, 22, p. 1495, 1993
The Journal of Organic Chemistry, 59, p. 4114, 1994 DOI: 10.1021/jo00094a021

3-Chlorobenzyl alcohol is synthesized via electrochemical reduction using cyclic voltammetric studies and constant current electrolysis, or produced by replacing the hydrogen atom of chlorobenzene with a hydroxymethyl group at the C(1) position[2][3]. The compound forms from the reaction of benzyl alcohol with atomic and molecular chlorine, or specifically with atomic chlorine[1].

[1]Sarzyński, D. S., & Majerz, I. (2024). Chemical Transformations of Benzyl Alcohol Caused by Atomic Chlorine. Molecules, 29(13), 3124. https://doi.org/10.3390/molecules29133124
[2]Saharan, R. (2022). Electro organic synthesis as green and sustainable approach for synthesis of chloro substituted benzyl alcohols. Journal of the Indian Chemical Society, 99(3), 100365. https://doi.org/10.1016/j.jics.2022.100365
[3]Arachchilage, A. P. W., Wang, Y., & Wang, F. (2011). A quantum mechanical study of bioactive 3-chloro-2,5-dihydroxybenzyl alcohol through substitutions. Theoretical Chemistry Accounts, 130(4-6), 965–979. https://doi.org/10.1007/s00214-011-1040-7