ChemicalBook CAS DataBase List 80-73-9

80-73-9

Name	1,3-Dimethyl-2-imidazolidinone
CAS	80-73-9
EINECS(EC#)	201-304-8
Molecular Formula	C5H10N2O
MDL Number	MFCD00003188
Molecular Weight	114.15
MOL File	80-73-9.mol

Synonyms

1,3-DIMETHYL-2-IMIDAZOLIDINONE 1,3-DIMETHYLIMIDAZOLIDIN-2-ONE 1,3-DIMETHYLIMIDAZOLIDINONE 1,3-DIMETHYLIMIDAZOLIDONE DIMETHYLETHYLENE UREA DMEU DMI N,N'-DIMETHYLETHYLENEUREA TIMTEC-BB SBB008346 1,3-dimethyl-2-imidazodinone 1,3-dimethyl-2-imidazolidinon 1,3-Dimethyl-2-imidazolidone 1,3-Dimethylethyleneurea 2-Imidazolidinone, 1,3-dimethyl- karbomostsem n,n’-dimethylimidazolidinone n,n’-dimethylimidazolidone N,N'-Dimethyl-2-imidazolidinone Rhonite 1 rhonite1

Chemical Properties

Appearance	Almost colorless, clear liquid
Melting point	8.2 °C
Boiling point	224-226 °C (lit.)
density	1.056 g/mL at 25 °C(lit.)
vapor pressure	<1 hPa (20 °C)
refractive index	n20/D 1.472(lit.)
Fp	220 °F
storage temp.	Store at +5°C to +30°C.
solubility	toluene: soluble(lit.)
form	Liquid
pka	-0.65±0.20(Predicted)
color	Clear
explosive limit	1.3-8.4%(V)
Water Solubility	freely soluble
Sensitive	Hygroscopic
Detection Methods	GC,NMR
Merck	14,3249
BRN	108808
Cosmetics Ingredients Functions	HAIR CONDITIONING HUMECTANT SKIN CONDITIONING
InChI	1S/C5H10N2O/c1-6-3-4-7(2)5(6)8/h3-4H2,1-2H3
InChIKey	CYSGHNMQYZDMIA-UHFFFAOYSA-N
SMILES	CN1CCN(C)C1=O
LogP	-0.3 at 25℃
CAS DataBase Reference	80-73-9(CAS DataBase Reference)
NIST Chemistry Reference	1,3-Dimethyl-2-imidazolidinone(80-73-9)
Storage Precautions	Store under nitrogen
EPA Substance Registry System	N,N'-Dimethylimidazolidinone (80-73-9)

Safety Data

Symbol(GHS)	GHS05,GHS07,GHS08
Signal word	Danger
Hazard statements	H302-H318-H361fd
Precautionary statements	P201-P202-P280-P301+P312-P305+P351+P338-P308+P313
Hazard Codes	Xn,Xi
Risk Statements	R21/22:Harmful in contact with skin and if swallowed . R38:Irritating to the skin. R41:Risk of serious damage to eyes. R36/38:Irritating to eyes and skin . less more
Safety Statements	S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36:Wear suitable protective clothing . S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . less more
RIDADR	UN 2810 6.1/PG 3
WGK Germany	3
RTECS	NJ0660000
F	3
Autoignition Temperature	305 °C
Hazard Note	Harmful/Irritant
TSCA	Yes
REACH Registrations	Active
HazardClass	6.1
PackingGroup	Ⅲ
HS Code	29332990
Storage Class	10 - Combustible liquids
Hazard Classifications	Acute Tox. 4 Oral Eye Dam. 1 Repr. 2
Toxicity	LD50 orally in Rabbit: 1261 mg/kg LD50 dermal Rabbit 986 mg/kg less more

Raw materials And Preparation Products

Hazard Information

Description

DMI, a high purity aprotic solvent, is composed of nitrogen containing five membered ring compound and widely recognized as an epoch making solvent. It is a colorless, transparent, high polar solvent with high thermal and chemical stability and non-corrosiveness. The material has a high boiling point of 222° C, a high flash point of 120° C (open method) / 95° C (close method), and a low melting point of 7.5° C.

Chemical Properties

Almost colorless, clear liquid

Uses

1,3-Dimethyl-2-imidazolidinone is used as a high-boiling polar aprotic solvent. It is used as a substitute solvent for toxic hexamethylphosphoramide. It finds application in detergents, dyestuffs, electronic materials and in the manufacture of polymers. It is involved in the preparation of 1,2-bis(trimethylsilyl)benzene. Further, it is utilized as a solvent during alfa-regioselective prenylation of imines. In addition to this, it constitutes the mobile phase during size-exclusion chromatographic analysis of cellulose.

Uses

DMI can be used in a variety of applications including detergents, dyestuffs, electronic materials and in the manufacture of polymers. Its versatility can be attributed to it. Of particular note are its excellent solubility for inorganic and organic compounds and high dielectric constant and solvation effect.

Definition

ChEBI: 1,3-Dimethyl-2-imidazolidinon is an imidazolidinone.

General Description

1,3-Dimethyl-2-imidazolidinone (DMI) is an imidazolidine derivative. It is reported to act as a promoter by minimizing the formation of dialkylation byproducts and accelerating the rate of monoalkylation of γ-butyrolactone. Conversion of CO₂ to form lower alcohols by homogeneous catalytic hydrogenation using DMI as solvent has been investigated.

Flammability and Explosibility

Nonflammable

Synthesis

136-84-5

80-73-9

Example 4: 320 g (2.2 mol) of 1,3-bis(hydroxymethyl)imidazolidin-2-one and 200 g (2.9 mol) of sodium formate were dissolved in 620 g (13.5 mol) of formic acid, and the reaction mixture was heated under reflux conditions for 8 hours. After completion of the reaction, 238 g of formic acid was removed by distillation under reduced pressure. To the residue 200 g of potassium carbonate was slowly added. After cooling, the crude product was separated by decantation and washed with a small amount of dichloromethane. Subsequently, the product was purified by vacuum distillation. 157 g of 1,3-dimethyl-2-imidazolidinone was collected in 63% yield at 90°C to 95°C and a pressure of 3 torr. The purity of the product was determined by gas chromatography (GC) and hydrogen nuclear magnetic resonance (1H-NMR) and confirmed to be >98%.

Toxics Screening Level

Due to a lack of available toxicity data the screening level is being set at default value of 0.1 μg/m3 with annual averaging.

References

[1] Patent: US4864026, 1989, A

Material Safety Data Sheet(MSDS)

Spectrum Detail

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