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624-49-7

Name Dimethyl fumarate
CAS 624-49-7
EINECS(EC#) 210-849-0
Molecular Formula C6H8O4
MDL Number MFCD00064438
Molecular Weight 144.13
MOL File 624-49-7.mol

Chemical Properties

Appearance fine white crystalline powder
Melting point  102-106 °C(lit.)
Boiling point  192-193 °C(lit.)
density  1,37 g/cm3
vapor pressure  5 hPa (25 °C)
refractive index  1.4062 (estimate)
Fp  192-193°C
storage temp.  Store at RT.
solubility  1.6g/l
form  Liquid
color  Clear colorless to faintly yellow
PH 4.0-6.0 (10g/l, H2O, 20℃)suspension
Stability: Stable. Incompatible with acids, bases, oxidizing agents, reducing agents.
Water Solubility  Soluble in water (1.6 mg/ml at 20°C), methanol (30-36 mg/ml), ethanol (10 mg/ml at 25°C), DMSO (29 mg/ml at 25°C), and DMF (~12 mg/ml).
Merck  14,4287
BRN  774590
Contact allergens
Dimethylfumarate, a strong irritant, is used as an industrial wide spectrum biocide in Asia and mainly in China, for textiles, leather, seeds, food, and cosmetic ingredients. It provoked a worldwide epidemic of severe contact dermatitis, initially from Chinese sofas sold in Finland, Great Britain, and France. It also induced severe burning and contact allergy due to shoes, and to contaminated clothing as well. This chemical, presents as is (white powder) or as tablets contained in little bags disposed in/or around the materials to protect, progressively evaporates and contaminates the environment. It is forbidden in the European Union since 2008
CAS DataBase Reference 624-49-7(CAS DataBase Reference)
NIST Chemistry Reference 2-Butenedioic acid (E)-, dimethyl ester(624-49-7)
EPA Substance Registry System 624-49-7(EPA Substance)

Safety Data

Hazard Codes  Xn
Risk Statements 
R21:Harmful in contact with skin.
R38:Irritating to the skin.
R41:Risk of serious damage to eyes.
R43:May cause sensitization by skin contact.
R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Statements 
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
RIDADR  UN 3077 9 / PGIII
WGK Germany  1
RTECS  EM6125000
TSCA  Yes
HS Code  29171990
Hazardous Substances Data 624-49-7(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: 2240 mg/kg LD50 dermal Rabbit 1250 mg/kg

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