67884-12-2

Martynoside protects ex vivo bone marrow cells from 5-fluorouracil (5-FU)-induced cell death and inflammation response by down-regulating the TNF signaling pathway[1].Martynoside is a potent antiestrogen in MCF-7 cells, increasing IGFBP3 levels

Estrogen receptor | ROS | Progestogen receptor

[1] Hong M, et al. Ex vivo and in vivo chemoprotective activity and potential mechanism of Martynoside against 5-fluorouracil-induced bone marrow cytotoxicity.?Biomed Pharmacother. 2021;138:111501. DOI:10.1016/j.biopha.2021.111501
[2] Papoutsi Z,et al. Acteoside and martynoside exhibit estrogenic/antiestrogenic properties.?J Steroid Biochem Mol Biol. 2006;98(1):63-71. DOI:10.1016/j.jsbmb.2005.07.005