740-33-0

Yellow crystals, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Scutellaria baicalensis.

Mosloflavon is a natural product derived from plant source th at finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

ChEBI: Mosloflavone is a member of flavonoids and an ether.

Mosloflavanone exhibits potent anti-EV71 activity by reducing visible cytopathic effects and suppressing virus replication during the initial infection phase. It also hinders the expression of the viral VP2 proteinthereby impeding viral capsid protein synthesis. AdditionallyMosloflavone demonstrates significant anti-inflammatory potential through the inhibition of TNF-α and IL-1βwith IC50 values of 16.4 μM and 6.4 μMrespectively. It shows a dose-dependent reduction in TNF-αIL-1βand iNOS levels in the supernatant of the mouse macrophage cell line J774A. This compound holds promise as a foundational element in the quest for treatments targeting inflammatory and immunomodulatory diseases.