41253-21-8

288-88-0

41253-21-8

General procedure for the synthesis of sodium 1,2,4-triazole from 1,2,4-triazole: To a three-necked flask equipped with a mechanical stirrer, an internal thermometer, and a reflux condenser, 200 mL of anhydrous methanol and 45 mL of a 30% methanol solution of sodium methanol (containing 0.25 mol of sodium methanol) were added, under dry nitrogen protection. At room temperature, 17.4 g (0.25 mol) of 1,2,4-triazole was added in batches. After completion of addition, the reaction mixture was heated to reflux temperature and stirred for 4 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. To the remaining oily residue was added 200 mL of dichloromethane and stirred at room temperature for 15 minutes. The precipitated solid product was collected by filtration to afford 22.5 g of sodium 1,2,4-triazolate (yield 98% of the theoretical value) as a colorless powder. The purity of the product was confirmed by 1H-NMR spectroscopy and no residue of the raw material 1,2,4-triazole was detected.