31252-42-3

CLEAR COLOURLESS TO YELLOW VISCOUS LIQUID

4-Benzylpiperidine was studied as acid corrosion inhibitor for iron. It was also used to study potential utility of dopamine-welective releaser as a treatment for cocaine dependence. In an assay of cocaine discrimination, 4-Benzylpiperidine had the most rapid onset and shortest duration of action.

Reactant for synthesis of:
Antiproliferatives
GABA uptake inhibitors
Pyridines
Histamine H3 antagonists
Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer′s and neuronal vascular diseases
Antiserotoninergic, antiplatelet, hemorheologic, antiarrythmic and antioxidant molecules via nucleophilic substitution

Reactant for synthesis of:
Antiproliferatives
GABA uptake inhibitors
Pyridines
Histamine H3 antagonists
Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer′s and neuronal vascular diseases
Antiserotoninergic, antiplatelet, hemorheologic, antiarrythmic and antioxidant molecules via nucleophilic substitution

4-Benzylpiperidine can be prepared by reacting 4-cyanopyridine with toluene. Catalytic hydrogenation of the pyridine ring then completes the synthesis.

Synthesis, p. 741, 1980 DOI: 10.1055/s-1980-29196

4-Benzylpiperidine inhibits the activity of rat brain monoamine oxidase-A and -B.