Uses
2-Bromo-6-fluorobenzoic acid is an intermediate, mainly used in the industries such as medicine, agricultural chemicals at present.
Synthesis
The synthesis and preparation method of the 2-bromo-6-fluorobenzoic acid comprises the following steps: by using o-fluorobenzonitrile as an initial raw material, carrying out nitrification, nitroreduction, bromization, diazo-deamination and hydrolysis to synthesize the 2-bromo-6-fluorobenzoic acid.
References
[1] Organic Letters, 2009, vol. 11, # 5, p. 1051 - 1054
[2] Australian Journal of Chemistry, 2016, vol. 69, # 3, p. 307 - 313
[3] Synthesis, 2005, # 4, p. 617 - 621
[4] Tetrahedron Letters, 1996, vol. 37, # 36, p. 6551 - 6554
[5] ChemMedChem, 2010, vol. 5, # 10, p. 1693 - 1696
