117-99-7

yellow crystalline powder

2-Hydroxybenzophenone was used to quantify the metabolites of unmethylated extracts from the supernatants of Pseudomonas acidovorans cultures grown on 1,1-diphenylethylene.
2-Hydroxybenzophenone forms copolymer 2-hydroxy, 3-allyl, 4,4′-dimethoxybenzophenone with methyl methacrylate.
It forms photostabilizer compounds with 2,2,6,6-tetramethylpiperidine under phase transfer catalysis conditions.
It reacts with 3-aminophenyl boronic acid to form macrocyclic boronates.

Preparation by Friedel–Crafts acylation of benzene in the presence of aluminium chloride,
? with 2-hydroxybenzoyl chloride (salicylic acid chloride), (52%), (39%), at temperature <60°;
? with o-anisoyl chloride. Demethylation occurred during the Friedel–Crafts acylation, especially in the presence of ferric chloride at 130–140°;
? with 2-ethoxybenzoyl chloride in a boiling water bath (42%).

Journal of the American Chemical Society, 76, p. 5469, 1954 DOI: 10.1021/ja01650a062
The Journal of Organic Chemistry, 32, p. 3844, 1967 DOI: 10.1021/jo01287a027