≤2mg/ml in ethanol;20mg/ml in DMSO;20mg/ml in dimethyl formamide
form
powder
pka
14.47±0.10(Predicted)
color
white to beige
Safety Information
Symbol(GHS)
Signal word
Danger
Hazard statements
H301:Toxic if swalloed
Precautionary statements
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
Description
ML-354 is an indole-based, proteinase-activated receptor 4 (PAR4) antagonist (IC50 = 140 nM) that exhibits 71-fold selectivity for PAR4 over PAR1 (IC50 = 10 μM) in isolated human platelets.