2,6-диметил-4-гептанон

Описание

2, 6-Dimethyl-4-heptanone, also known as diisobutyl ketone, belongs to the family of ketones, being a flavoring ingredient. It can also be used as the extraction solvent for the determination of ten trace metals (V, Cr, Fe, Co, Ni, Cu, Zn, Mo, Cd, Pb) in aqueous samples with plasma atomic emission spectrometry. Similar logic can also be applied to the measurement of phosphorus using 2, 6-dimethyl-4-heptanone as the extraction agent. It is also an important organic solvent widely used as industrial intermediates.

Химические свойства

5-Methyl-3-heptanone is a colorless liquid with low solubility in water (0.3 wt %); water is poorly soluble in the ketone (0.9 wt %). 5-Methyl-3-heptanone is highly soluble in common organic solvents.

Физические свойства

Clear, colorless liquid with a mild, sweet, ether-like odor. Odor threshold concentration is 0.11 ppm (quoted, Amoore and Hautala, 1983).

Вхождение

Reported found in baked potato and wheaten bread.

Использование

2,6-Dimethyl-4-heptanone is used as a coating solvent. It is an active component of mint oil. It acts as a dispersant for organosol type resins. It is involved in the antigerminative treatment of bulbs and tubers. Further, it is used as a solvent for nitrocellulose. In addition to this, it acts as an intermediate in the preparation of inhibitors, active pharmaceutical ingredients and dyes.

Методы производства

Diisobutyl ketone is produced by hydrogenation of phorone or by metal-catalyzed decomposition of isovaleric acid.It is also a by-product in the manufacture of methyl isobutyl ketone.

Общее описание

A clear colorless liquid. Flash point 140°F. Less dense than water and insoluble in water. Vapors heavier than air.

Реакции воздуха и воды

Flammable. Insoluble in water.

Профиль реактивности

2,6-Dimethyl-4-heptanone may attack some plastics. 2,6-Dimethyl-4-heptanone reacts with oxidizers.

Угроза здоровью

Inhalation of vapor causes irritation of nose and throat. Ingestion causes irritation of mouth and stomach. Vaporirritates eyes. Contact with liquid irritates skin.

Химическая реактивность

Reactivity with Water No reaction; Reactivity with Common Materials: May attack some forms of plastics; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

Профиль безопасности

Moderately toxic by ingestion and inhalation. Mddly toxic by skin contact. Human systemic effects by inhalation: headache, nausea or vomiting, and unspecified eye effects. An eye and skin irritant. Narcotic in high concentrations. Flammable liquid when exposed to heat or flame; can react with oxidizing materials. To fight fire, use Con, dry chemical, water spray, mist or fog. When heated to decomposition it emits acrid smoke and fumes. See also KETONES.

Экологическая судьба

Biological. Using the BOD technique to measure biodegradation, the mean 5-d BOD value (mM BOD/mM diisobutyl ketone) and ThOD were 4.86 and 37.4%, respectively (Vaishnav et al., 1987).
Chemical/Physical. Diisobutyl ketone will not hydrolyze because it has no hydrolyzable functional group.
At an influent concentration of 300 mg/L, treatment with GAC resulted in nondetectable concentrations in the effluent. The adsorbability of the carbon used was 60 mg/g carbon (Guisti et al., 1974).

Утилизация отходов

Incineration, molten metal salt destruction.

использованная литература

Bone, K. M., and W. D. Hibbert. "Solvent extraction with ammonium pyrrolidinedithiocarbamate and 2,6-dimethyl-4-heptanone for the determination of trace metals in effluents and natural waters." Analytica Chimica Acta 107.JUN(1979):219-229.
Miyazaki, Akira, A. Kimura, and Y. Umezaki. "Determination of ng ml-1 levels of phosphorus in waters by diisobutyl ketone extraction and inductively coupled plasma atomic emission spectrometry." Analytica Chimica Acta 127.96(1981):93-101.
Zhang, Fagen, et al. "Comparative metabolism and pharmacokinetics of diisobutyl ketone and diisobutyl carbinol in male SD rats." Toxicology Letters 232.1(2015):175-181.