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Bromfenac Sodium
- русский язык имя
- английское имяBromfenac Sodium
- CAS №120638-55-3
- CBNumberCB82130312
- ФормулаC15H11BrNNaO3
- мольный вес356.15
- EINECS695-342-6
- номер MDLMFCD23843787
- файл Mol120638-55-3.mol
химическое свойство
Температура плавления | 268-270°C (dec.) |
температура хранения | Refrigerator |
растворимость | DMSO: ≥ 100 mg/mL (260.98 mM); Water: ≥ 100 mg/mL (260.98 mM) |
форма | Solid |
цвет | Light yellow to yellow |
FDA UNII | 8ECV571Y37 |
Bromfenac Sodium химические свойства, назначение, производство
Описание
Duract was launched in the US as a potent, orally-active, long lasting peripheral analgesic with antiinflammatory properties. It is structurally similar to ketoprofen and diclofenac and can be prepared in three steps from 2-amino-4’-bromophenone using Gassman’s oxindole synthesis. Duract’s biological effects are a result of its ability to reduce prostaglandin production through inhibition of cyclooxygenase. As a 4-bromo derivative of Amfenac, this modification increased the duration of analgesic activity and antiinflammatory potency. It was also free of any CNS, cardiovascular or autonomic effects. In comparison, 5 mg of Duract was equipotent to 650 mg of ASA and 25 mg was slightly more potent than 400 mg of Ibuprofen.Химические свойства
Yellow SolidИспользование
Bromfenac is a non-steroidal anti-inflammatory agent.Определение
ChEBI: The sesquihydrate of the sodium salt of bromfenac. It is used for the management of ocular pain and treatment of postoperative inflammation in patients who have undergone cataract extraction.Bromfenac Sodium поставщик
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