ТРИИЗОПРОПИЛФОСФИТ

Химические свойства

Colorless liquid; characteristic odor. Miscible with most common organic solvents; insoluble in water; hydrolyzes slowly in water; exposure to air should be minimum; high thermal stability. Combustible.

Использование

Triisopropyl phosphite can be used as a reactant:

• With Ru-based indenylidene complexes to form 1^st generation complexes for metathesis reactions.
• In Perkow-type reaction to synthesize compounds containing polarized carbon-carbon double bonds.
• For the synthesis of phosphonohydrazines by reacting with arylamines and isoamyl nitrite.

It can also be used as an alternative to triphenylphosphine in Mitsunobu reaction to facilitate the isolation of products.

Методы очистки

Distil it from sodium, under vacuum, through a column packed with glass helices. (This removes any dialkyl phosphonate.) [Ford-Moore & Williams J Chem Soc 1465 1947, Arbuzov Chem Ber 38 1171 1905, see Verkade & Coskren in Organo Phosphorus Compound (Kosolapoff & Maier eds) Wiley Vol 2 pp 1-187 1972, Beilstein 1 IV 1476.]