![ChemicalBook](https://m.chemicalbook.com/Scripts/New/img/logo.png)
![КАПТАН структурированное изображение](/CAS/GIF/133-06-2.gif)
КАПТАН
- английское имяCaptan
- CAS №133-06-2
- CBNumberCB4367608
- ФормулаC9H8Cl3NO2S
- мольный вес300.59
- EINECS205-087-0
- номер MDLMFCD00041811
- файл Mol133-06-2.mol
Температура плавления | 178°C |
Температура кипения | 314.2°C (rough estimate) |
плотность | 1.74 |
давление пара | 1.0 x 10-5 Pa (25 °C) |
показатель преломления | 1.6360 (estimate) |
Fp | 2 °C |
температура хранения | Inert atmosphere,Room Temperature |
растворимость | Chloroform: Slightly Soluble,Methanol: Slightly Soluble |
Растворимость в воде | 3.3 mg l-1 (25 °C) |
пка | -2.68±0.20(Predicted) |
форма | Amorphous Powder |
цвет | White, beige |
Мерк | 14,1772 |
БРН | 234872 |
Пределы воздействия | ACGIH TLV: TWA 5 mg/m3. |
Стабильность | Stable. Incompatible with strong bases, strong oxidizing agents. |
LogP | 2.57 at 25℃ |
Непрямые добавки, используемые в веществах, контактирующих с пищевыми продуктами | CAPTAN |
FDA 21 CFR | 310.545 |
Справочник по базе данных CAS | 133-06-2(CAS DataBase Reference) |
Рейтинг продуктов питания EWG | 7-10 |
FDA UNII | EOL5G26Q9F |
Предложение 65 Список | Captan |
МАИР | 3 (Vol. 30, Sup 7) 1987 |
Справочник по химии NIST | Captan(133-06-2) |
Система регистрации веществ EPA | Captan (133-06-2) |
Коды опасности | T;N,N,T,Xn,F | |||||||||
Заявления о рисках | 23-40-41-43-50-36-20/21/22-11 | |||||||||
Заявления о безопасности | 26-29-36/37/39-45-61-36/37-16 | |||||||||
РИДАДР | UN 3077/9099 | |||||||||
OEB | B | |||||||||
OEL | TWA: 5 mg/m3 | |||||||||
WGK Германия | 2 | |||||||||
RTECS | GW5075000 | |||||||||
Класс опасности | 6.1 | |||||||||
Группа упаковки | III | |||||||||
кода HS | 29309090 | |||||||||
Банк данных об опасных веществах | 133-06-2(Hazardous Substances Data) | |||||||||
Токсичность | LD50 orally in rats: 9000 mg/kg (Bridges) | |||||||||
NFPA 704: |
|
рисовальное письмо(GHS)
-
рисовальное письмо(GHS)
-
сигнальный язык
опасность
-
вредная бумага
H318:При попадании в глаза вызывает необратимые последствия.
H317:При контакте с кожей может вызывать аллергическую реакцию.
H400:Чрезвычайно токсично для водных организмов.
H351:Предполагается, что данное вещество вызывает раковые заболевания.
H331:Токсично при вдыхании.
-
оператор предупредительных мер
P201:Беречь от тепла, горячих поверхностей, искр, открытого огня и других источников воспламенения. Не курить.
P273:Избегать попадания в окружающую среду.
P280:Использовать перчатки/ средства защиты глаз/ лица.
P304+P340+P311:ПРИ ВДЫХАНИИ: Свежий воздух, покой. Обратиться за медицинской помощью.
P305+P351+P338+P310:ПРИ ПОПАДАНИИ В ГЛАЗА: Осторожно промыть глаза водой в течение нескольких минут. Снять контактные линзы, если Вы ими пользуетесь и если это легко сделать. Продолжить промывание глаз. Немедленно обратиться за медицинской помощью.
P308+P313:ПРИ подозрении на возможность воздействия обратиться за медицинской помощью.
КАПТАН химические свойства, назначение, производство
Описание
Captane is a pesticide belonging to the thiophtalimide group, mainly affecting agricultural workers. As a sensitizer and photosensitizer, it can induce contact urticaria. Its is used as a fungicide and a bacteriostatic agent in cosmetics and toiletries, particularily in shampoos. Cases of contact dermatitis were reoprted in painters, polishers and varnishers.Химические свойства
Captan, when pure, is a colorless crystalline solid. The technical grade is a cream to yellow powder with a strong odor. It is commonly dissolved in a “carrier” which may be combustible.Использование
Captan is used to control a wide range of fungal diseases on many crops.Определение
ChEBI: A dicarboximide that is 3a,4,7,7a-tetrahydrophthalimide in which the hydrogen attached to the nitrogen is replaced by a trichloromethyl group. A non-systemic fungicide introduced in the 1950s, it is widely used for the control of fungal diseases in fruits, vegetables, and ornamental crops.Общее описание
Captan is a white solid dissolved in a liquid carrier. Captan is a water emulsifiable liquid. Captan can cause illness by inhalation, skin absorption and/or ingestion. The primary hazard of Captan is that Captan poses a threat to the environment. In case of release immediate steps should be taken to limit its spread to the environment. Since Captan is a liquid Captan can easily penetrate the soil to contaminate groundwater. Captan is used as a fungicide.Реакции воздуха и воды
Slowly hydrolyzed in aqueous neutral and acidic media. Rapidly hydrolyzed in alkaline media. Insoluble in water.Профиль реактивности
Captan decomposes at or near the melting point. Captan is incompatible with strong alkaline and oxidizing materials, sulfur and (sulfur + moisture).Опасность
A questionable carcinogen. A skin irritant. Avoid inhalation of dust or spray mist. Avoid con- tamination of feed and foodstuffs.Угроза здоровью
Vapor irritates eyes. Ingestion causes depression, lachrymation, labored respiration, diarrhea.Пожароопасность
Special Hazards of Combustion Products: Irritating and toxic gases are produced in a fire; they may include sulfur dioxide, hydrogen chloride, phosgene, and oxides of nitrogen.Сельскохозяйственное использование
Fungicide: Most uses of captan on food crops in the United States have been canceled since 1989. It is still used in apple production, almonds and strawberries. It is often applied to packing and shipping boxes for fruits and vegetables. Captan is rapidly degraded in natural soil by chemical as well as biologic means (estimated half-life, days to weeks). It is also used as a preservative for awnings, draperies and leather, as a root dip and seed treatment. It is also added to paints, wallpaper paste, plastic and leather goods. There are over 320 federally registered pesticide products that contain captan.Торговое название
AACAPTAN®; AGROSOL S®[C]; AGROX® 2-WAY and 3-WAY[C]; AMERCIDE®; APRON®[C]; BEISTERGARD®; BANGTON®; BEAN SEED PROTECTANT®; CAPTANCAPTENEET® 26,538; CAPTAF®; CAPTAF®; CAPTAN® 50 W; CAPTAN SC®; CAPTEX®; CRIPTAN®; ESSO® FUNGICIDE 406; FLIT® 406; FUNGUS BAN® TYPE II; FUNGICIDE 406®; GLYODEX® 37-22; GRANOX PFM®; GUSTAFSON CAPTAN 30-DD; HEXACAP®; ISOTOX SEED TREATER® “D” and “F”; KAPTAN®; MALIPUR®; MERPAN®; MICRO-CHECK® 12; MIOSTAT®; NERACID®; ORTHOCIDE®; OSOCIDE®; POTATO SEED PIECE PROTECTANT®; SR 406®; STAUFFER CAPTAN®; TRIMEGOL®; VANICIDE®; VANICIDE® P-75; VANICIDE® 89; VANICIDE® 89RE; VANGARD® K; VANGUARD® K; VONDCAPTAN®Контактные аллергены
A pesticide, belonging to the thiophthalimide group, mainly affects agricultural workers. Being sensitizer and photosensitizer, it can induce contact urticaria. It is used as a fungicide and a bacteriostatic agent in cosmetics and toiletries, particularly in shampoos. Cases of contact dermatitis were reported in painters, polishers, and varnishersПрофиль безопасности
Poison by intraperitoneal route. Moderately toxic to humans by ingestion. Moderately toxic experimentally by ingestion and inhalation routes. Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental tumorigenic and neoplastigenic data. Human mutation data reported. When heated to decomposition it emits toxic fumes of Cl-, SOx, and NOx.Возможный контакт
Captan is a thiophthalimide compound used as an agricultural fungicide for field crops and storage of produce and also as a preservative in cosmetics; an overthe-counter-drug.Экологическая судьба
Biological. In water, captan reacted with the fungicide L-cysteine forming a compound with an absorption maximum of 272 μm which was identified as 2-thiazolidinethione-4- carboxylic acid. In addition, tetrahydrophthalimide also formed (Lukens and Sisler, 1958).Soil. The half-lives of captan in soil ranged from 3.5 days (pH 6.4, moisture content 17.5%) to >50 days (pH 6.2, moisture content 1.6%) (Burchfield, 1959). The half-lives of captan in a sandy loam, clay loam and an organic amended soil under non-sterile conditions were 10–354, 3.4–587 and 7.0–213 days, respectively, while under sterile conditions the half-lives were 9.4–373, 2.8–303 and 4.3–191 days, respectively (Schoen and Winterlin, 1987).
Chemical/Physical. Captan undergoes hydrolysis under neutral or alkaline conditions yielding 4-cyclohexene-1,2-dicarboximide, carbon dioxide, hydrogen chloride and sulfur (Wolfe et al., 1976a). The estimated hydrolysis half-life of captan in a phosphate buffer solution at pH 7.07 and 28–29°C is 2.96 hours. Between the pH range 2 to 6, the estimated hydrolysis half-life is 10.70 hours (Wolfe et al., 1976a). Worthing and Hance (1991)reported hydrolysis half-lives of 8.3–32.4 hours and <2 minutes at pH values 7 and 10, respectively.
Decomposes at or near the melting point (Hartley and Kidd, 1987).
Метаболический путь
Captan contains an unstable trichloromethylthio (sulfenyl) moiety that has been shown to undergo rapid hydrolytic and metabolic degradation to tetrahydrophthalimide (2).Studies of the decomposition of [35S]captanw ith conidia of Neurospora crassa (Richmond and Somers, 1968) showed that the trichloromethythio moiety can be transferred to the sulfur atoms of thiols such as cysteine and glutathione (Richmond and Somers, 1966). Thus, in the presence of thiols such as glutathione, captan is cleaved at the N-S bond to form thiophosgene (3) and other gaseous products such as hydrogen sulfide, hydrogen chloride and carbonyl sulfide (see Scheme 2). Thiophosgene is rapidly hydrolysed by water. The trichlormethythio group and thiophosgene are believed to be intermediates in the formation of thiazolidine-2- thione-4-carboxylic acid (4) which is an addition product with cysteine. A thiazolidine derivative of glutathione is also formed (5). Biotransformation of captan in mammals generates primarily thiophosgene (3) and tetrahydrophthalimide (2). Tetrahydrophthalimide (2) and various of its hydroxylated derivatives are excreted in the urine. The thiophosgeneglutathione adduct (5) subsequently degrades and is eventually excreted in the urine as 2-thiazolidinethione-4-carboxylic acid (4).
Перевозки
UN2773 Phthalimide derivative pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.Несовместимости
Incompatible with tetraethyl pyrophosphate, parathion. Keep away from strong alkaline materials(e.g., hydrated lime) as captan may become unstable. May react with water releasing hydrogen chloride gas. Corrosive to metals in the presence of moisture.Утилизация отходов
Captan decomposes fairly readily in alkaline media (pH >8). It is hydrolytically stable at neutral or acid pH but decomposes when heated alone at its freezing/melting point. Alkaline hydrolysis is recommendedКАПТАН запасные части и сырье
КАПТАН поставщик
поставщик | телефон | страна | номенклатура продукции | благоприятные условия |
---|---|---|---|---|
+8613573296305 | China | 297 | 58 | |
+86-0311-87836622 +86-17333973358 |
China | 8073 | 58 | |
+86-0371-55170693 +86-19937530512 |
China | 21667 | 55 | |
+86-0371-86658258 +8613203830695 |
China | 29889 | 58 | |
18871490254 | CHINA | 28180 | 58 | |
+86-19930503282 | China | 8821 | 58 | |
18853181302 | CHINA | 5909 | 58 | |
+86-023-6139-8061 +86-86-13650506873 |
China | 39916 | 58 | |
+8618523575427 | China | 49392 | 58 | |
+86 13288715578 +8613288715578 |
China | 12449 | 58 |